Abstract:
Polysaccharides have drawn a lot of attention due to their potential as carriers for drugs and other bioactive chemicals. In drug delivery systems, natural macromolecules such as polysaccharides are widely utilized as polymers. This utilization extends to various polysaccharides employed in the development of nanoparticles for medicinal administration, with the goal of enhancing therapeutic efficacy while minimizing side effects. This study not only offers an overview of the existing challenges faced by these materials but also provides detailed information on key polysaccharides expertly engineered into nanoparticles. Noteworthy examples include Bael Fruit Gum, Guar Gum, Pectin, Agar, Cellulose, Alginate, Chitin, and Gum Acacia, each selected for their distinctive properties and strategically integrated into nanoparticles. The exploration of these natural macromolecules illuminates their diverse applications and underscores their potential as effective carriers in drug delivery systems. By delving into the unique attributes of each polysaccharide, this review aims to contribute valuable insights to the ongoing advancements in nanomedicine and pharmaceutical technologies. The overarching objective of this review research is to assess the utilization and comprehension of polysaccharides in nanoapplications, further striving to promote their continued integration in contemporary therapeutics and industrial practices.
摘要:
多糖由于其作为药物和其他生物活性化学物质的载体的潜力而引起了很多关注。在药物递送系统中,天然大分子如多糖被广泛用作聚合物。这种利用延伸到用于药物施用的纳米颗粒的开发中使用的各种多糖。目的是提高治疗效果,同时尽量减少副作用。这项研究不仅概述了这些材料面临的现有挑战,而且还提供了有关关键多糖的详细信息。值得注意的例子包括Bael水果口香糖,瓜尔胶,果胶,琼脂,纤维素,海藻酸盐,甲壳素,和金合欢胶,每个人都因其独特的特性而选择,并战略性地整合到纳米颗粒中。这些天然大分子的探索阐明了它们的多种应用,并强调了它们作为药物递送系统中有效载体的潜力。通过深入研究每种多糖的独特属性,这篇综述旨在为纳米医学和制药技术的持续进步提供有价值的见解。本综述研究的总体目标是评估纳米应用中多糖的利用和理解,进一步努力促进他们继续融入当代治疗和工业实践。