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Abstract：
Diseases in young calves received as emergencies are often associated with hypovolemic and/or septic shocks. The objectives of our study were to (1) assess the correlation between clinical hemodynamic parameters and blood L-lactates (LAC), systolic blood pressure (SBP), and the shock index (SI) recorded upon arrival; and (2) to evaluate how these parameters were related to short-term outcomes in calves under 4 months of age presented as emergencies. We conducted a single-observer prospective observational study on calves aged from 1 day to 4 months, presented to the Veterinary Clinic for Ruminants of Liège from December 2020 to May 2022. Forty-five calves were included in the study. The statistical analysis revealed a significant correlation between LAC and heart rate (r = 0.570; p < 0.05) and LAC and SI (r = 0.373; p < 0.05). A high LAC value at admission was significantly associated with a negative outcome (death) (p < 0.05). In calves suffering from obstructive digestive diseases, the SI was related to the outcome and the analysis indicated a cut-off value of 1.13 (Se = 0.77, Spe = 1). In conclusion, in our study, the initial blood L-lactate value was correlated with heart rate, the shock index, and the clinical shock score, and admission hyperlactatemia was associated with a poor prognosis in calves under 4 months of age. In this cohort, the shock index in calves suffering from digestive diseases was linked with mortality.
摘要：
作为紧急情况接受的小牛疾病通常与低血容量和/或败血性休克有关。我们研究的目的是（1）评估临床血液动力学参数与血液L-乳酸（LAC）之间的相关性，收缩压（SBP），和到达时记录的休克指数（SI）；（2）评估这些参数如何与4月龄以下小牛的短期结局相关。我们对1天至4个月大的小牛进行了单观察者前瞻性观察研究，于2020年12月至2022年5月提交列日反刍动物兽医诊所。该研究包括45只小牛。统计分析显示LAC与心率(r=0.570;p<0.05)、LAC与SI(r=0.373;p<0.05)之间存在显著相关性。入院时高LAC值与阴性结果（死亡）显着相关（p<0.05）。在患有阻塞性消化系统疾病的小牛中，SI与结果相关,分析显示临界值为1.13(Se=0.77,Spe=1).总之,在我们的研究中,初始血L-乳酸值与心率相关，冲击指数，和临床休克评分，入院高乳酸血症与4月龄以下小牛的预后不良相关。在这个队列中，患有消化系统疾病的小牛的休克指数与死亡率有关。
