PDF(Pubmed)
Abstract：
The uterus is a highly innervated organ, and during labor, this innervation is at its highest level. Oxytocinergic fibers play an important role in labor and delivery and, in particular, the Lower Uterine Segment, cervix, and fundus are all controlled by motor neurofibers. Oxytocin is a neurohormone that acts on receptors located on the membrane of the smooth cells of the myometrium. During the stages of labor and delivery, its binding causes myofibers to contract, which enables the fundus of the uterus to act as a mediator. The aim of this study was to investigate the presence of oxytocinergic fibers in prolonged and non-prolonged dystocic delivery in a cohort of 90 patients, evaluated during the first and second stages of labor. Myometrial tissue samples were collected and evaluated by electron microscopy, in order to quantify differences in neurofibers concentrations between the investigated and control cohorts of patients. The authors of this experiment showed that the concentration of oxytocinergic fibers differs between non-prolonged and prolonged dystocic delivery. In particular, in prolonged dystocic delivery, compared to non-prolonged dystocic delivery, there is a lower amount of oxytocin fiber. The increase in oxytocin appeared to be ineffective in patients who experienced prolonged dystocic delivery, since the dystocic labor ended as a result of the altered presence of oxytocinergic fibers detected in this group of patients.
摘要：
子宫是一个高度神经支配的器官,在分娩过程中，这种神经支配处于最高水平。氧化纤维素纤维在分娩和分娩中起着重要作用，特别是,子宫下段,子宫颈,和眼底都是由运动神经纤维控制的。催产素是一种神经激素，作用于位于子宫肌层光滑细胞膜上的受体。在劳动和分娩阶段，它的结合导致肌纤维收缩，这使得子宫底可以充当中介。这项研究的目的是调查在90名患者的队列中，延长和非延长的分娩难中存在催氧纤维。在第一和第二阶段进行评估。收集子宫肌层组织样本并通过电子显微镜进行评估，为了量化研究和对照组患者之间神经纤维浓度的差异。该实验的作者表明，在非延长和延长的阵痛传递之间，催氧能纤维的浓度不同。特别是,在长时间的分娩中，与非长期分娩困难相比，催产素纤维含量较低。催产素的增加在经历了长时间分娩困难的患者中似乎无效。因为在这组患者中检测到的催产素能纤维的存在改变导致分娩困难。
