PDF(Pubmed)
Abstract：
OBJECTIVE: Although participants in 7 T magnetic resonance (MR) studies tolerate ultra-high field (UHF) well, subjectively experienced short-term effects, such as dizziness, inconsistent movement, nausea, or metallic taste, are reported. Evidence on subjectively experienced short-term effects in multiple exposures to UHF MR is scarce. The purpose of this study is to investigated experience of short-term effects, and occurrence of motion in healthy subjects exposed to seven weekly 7 T MR examinations.
METHODS: A questionnaire on short-term effects was completed by participants in an fMRI motor skill study. Seven UHF MR examinations were conducted over 7 weeks (exposure number: 1 to 7). Changes of experienced short-term effects were analyzed. Motion in fMRI images was quantified.
RESULTS: The questionnaire was completed 360 times by 67 participants after one to seven 7T MR examinations. Logistic mixed model analysis showed a significant association between dizziness, inconsistent movement, nausea, and headache and the examination numbers (p<0.03). Exposure to repeated examinations had no significant effect on peripheral nerve stimulation (PNS) or motion of the subjects. The overall experience of a 7T examination improved significantly (p<0.001) with increasing examination numbers.
CONCLUSIONS: During multiple 7T examinations, subjects adapt to the strong static field. The short-term effects dizziness, inconsistent movement, nausea, and headache decrease over time as the MR sessions continue and experienced comfort increases. There was no significant difference in motion during the multiple fMRI examinations.
METHODS: A questionnaire on short-term effects was completed by participants in an fMRI motor skill study. Seven UHF MR examinations were conducted over 7 weeks (exposure number: 1 to 7). Changes of experienced short-term effects were analyzed. Motion in fMRI images was quantified.
RESULTS: The questionnaire was completed 360 times by 67 participants after one to seven 7T MR examinations. Logistic mixed model analysis showed a significant association between dizziness, inconsistent movement, nausea, and headache and the examination numbers (p<0.03). Exposure to repeated examinations had no significant effect on peripheral nerve stimulation (PNS) or motion of the subjects. The overall experience of a 7T examination improved significantly (p<0.001) with increasing examination numbers.
CONCLUSIONS: During multiple 7T examinations, subjects adapt to the strong static field. The short-term effects dizziness, inconsistent movement, nausea, and headache decrease over time as the MR sessions continue and experienced comfort increases. There was no significant difference in motion during the multiple fMRI examinations.
摘要：
目的：尽管7T磁共振（MR）研究的参与者对超高场（UHF）的耐受性良好，主观上经历了短期影响，如头晕，不一致的运动，恶心,或金属味，已报告。关于多次暴露于UHFMR的主观经历的短期影响的证据很少。这项研究的目的是调查短期效应的经验，以及每周7次接受7次7TMR检查的健康受试者的运动情况。
方法：一项fMRI运动技能研究的参与者完成了短期影响的问卷调查。在7周内进行了7次UHFMR检查（暴露次数：1至7）。分析了经历的短期效应的变化。对fMRI图像中的运动进行量化。
结果：67名参与者在1至7次7TMR检查后完成了360次问卷。Logistic混合模型分析显示头晕，不一致的运动，恶心,头痛和检查次数（p<0.03）。暴露于重复检查对周围神经刺激（PNS）或受试者的运动没有显着影响。7T检查的总体经验随着检查次数的增加而显着改善（p<0.001）。
结论：在多次7T检查中，受试者适应强静态场。短期影响头晕，不一致的运动，恶心,随着MR会话的继续和舒适度的增加，头痛会随着时间的推移而减少。在多次fMRI检查期间，运动没有显着差异。
方法：一项fMRI运动技能研究的参与者完成了短期影响的问卷调查。在7周内进行了7次UHFMR检查（暴露次数：1至7）。分析了经历的短期效应的变化。对fMRI图像中的运动进行量化。
结果：67名参与者在1至7次7TMR检查后完成了360次问卷。Logistic混合模型分析显示头晕，不一致的运动，恶心,头痛和检查次数（p<0.03）。暴露于重复检查对周围神经刺激（PNS）或受试者的运动没有显着影响。7T检查的总体经验随着检查次数的增加而显着改善（p<0.001）。
结论：在多次7T检查中，受试者适应强静态场。短期影响头晕，不一致的运动，恶心,随着MR会话的继续和舒适度的增加，头痛会随着时间的推移而减少。在多次fMRI检查期间，运动没有显着差异。
