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Abstract：
BACKGROUND: Hemangiomas are a relatively common type of tumor in humans and animals. Various subtypes of hemangiomas have been described in the literature. The classification methods for hemangiomas differ between human and veterinary medicine, and the basis for tumor classification can be found in the literature.
METHODS: This study describes a tumor in the subcutaneous tissue of the right dorsum of an artificially rescued juvenile Chinese pangolin. Computed tomography (CT) examination yielded the preliminary diagnosis of a vascular malformation, and surgery was performed to resect the tumor. Histopathological examination showed that the tumor mainly was consisted of adipose tissue, capillaries, and spindle cells in the fibrous stroma. Immunohistochemistry showed the positive expression of CD31, CD34, α-SMA, GLUT1 and WT-1 in the tumor tissue, and the tumor was eventually diagnosed as an infantile haemangioma.
CONCLUSIONS: The final diagnosis of infantile hemangioma was depended on the histopathological immunohistochemical and CT examination of the neoplastic tissue. This is the first report of infantile hemangioma in a critically endangered species Chinese pangolin.
METHODS: This study describes a tumor in the subcutaneous tissue of the right dorsum of an artificially rescued juvenile Chinese pangolin. Computed tomography (CT) examination yielded the preliminary diagnosis of a vascular malformation, and surgery was performed to resect the tumor. Histopathological examination showed that the tumor mainly was consisted of adipose tissue, capillaries, and spindle cells in the fibrous stroma. Immunohistochemistry showed the positive expression of CD31, CD34, α-SMA, GLUT1 and WT-1 in the tumor tissue, and the tumor was eventually diagnosed as an infantile haemangioma.
CONCLUSIONS: The final diagnosis of infantile hemangioma was depended on the histopathological immunohistochemical and CT examination of the neoplastic tissue. This is the first report of infantile hemangioma in a critically endangered species Chinese pangolin.
摘要：
背景：血管瘤是人类和动物中相对常见的肿瘤类型。文献中已经描述了血管瘤的各种亚型。血管瘤的分类方法在人类和兽医学之间有所不同，肿瘤分类的依据可以在文献中找到。
方法：本研究描述了人工抢救的中国幼年穿山甲右背部皮下组织中的肿瘤。计算机断层扫描（CT）检查可初步诊断为血管畸形，手术切除肿瘤。组织病理学检查显示肿瘤主要由脂肪组织组成，毛细血管,和纤维基质中的梭形细胞。免疫组化显示CD31、CD34、α-SMA、GLUT1和WT-1在肿瘤组织中，肿瘤最终被诊断为婴儿血管瘤。
结论：婴儿血管瘤的最终诊断取决于肿瘤组织的组织病理学免疫组化和CT检查。这是极度濒危物种中国穿山甲中婴儿血管瘤的首次报道。
方法：本研究描述了人工抢救的中国幼年穿山甲右背部皮下组织中的肿瘤。计算机断层扫描（CT）检查可初步诊断为血管畸形，手术切除肿瘤。组织病理学检查显示肿瘤主要由脂肪组织组成，毛细血管,和纤维基质中的梭形细胞。免疫组化显示CD31、CD34、α-SMA、GLUT1和WT-1在肿瘤组织中，肿瘤最终被诊断为婴儿血管瘤。
结论：婴儿血管瘤的最终诊断取决于肿瘤组织的组织病理学免疫组化和CT检查。这是极度濒危物种中国穿山甲中婴儿血管瘤的首次报道。
