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Abstract：
BACKGROUND: Infection by Dialister micraerophilus, an obligate anaerobic gram-negative bacillus, has rarely been described, and its clinical characteristics remain unclear.
METHODS: We report a case of bacteremia caused by D. micraerophilus, Enterocloster clostridioformis, and Eggerthella lenta in a 47-year-old woman, associated with pyometra. D. micraerophilus was identified using 16S rRNA gene sequencing and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. D. micraerophilus was detected by polymerase chain reaction using D. micraerophilus-specific primers and E. clostridioformis and E. lenta was isolated from the drainage pus sample obtained from the pyometra uterus. The patient achieved a cure after abscess drainage and 2-week antibiotic treatment.
CONCLUSIONS: To the best of our knowledge, this is the first report of D. micraerophilus bacteremia. D. micraerophilus may be associated with gynecological infections. Clinicians should consider both oral and gynecological sites when searching to identify the focus of D. micraerophilus infection.
METHODS: We report a case of bacteremia caused by D. micraerophilus, Enterocloster clostridioformis, and Eggerthella lenta in a 47-year-old woman, associated with pyometra. D. micraerophilus was identified using 16S rRNA gene sequencing and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. D. micraerophilus was detected by polymerase chain reaction using D. micraerophilus-specific primers and E. clostridioformis and E. lenta was isolated from the drainage pus sample obtained from the pyometra uterus. The patient achieved a cure after abscess drainage and 2-week antibiotic treatment.
CONCLUSIONS: To the best of our knowledge, this is the first report of D. micraerophilus bacteremia. D. micraerophilus may be associated with gynecological infections. Clinicians should consider both oral and gynecological sites when searching to identify the focus of D. micraerophilus infection.
摘要：
背景：Dialistermicraerophilus感染，一种专性厌氧革兰阴性杆菌,很少被描述，其临床特征仍不清楚。
方法：我们报告一例由嗜黑D.肠表梭状芽孢杆菌,和一个47岁的女人的Eggerthellalenta，与子宫积脓有关。使用16SrRNA基因测序和基质辅助激光解吸电离飞行时间质谱鉴定了嗜微乳杆菌。使用D.micraerphilus特异性引物通过聚合酶链反应检测D.micraerophilus，并从从子宫积脓获得的引流脓液样品中分离出梭状芽孢杆菌和E.lenta。脓肿引流和2周抗生素治疗后，患者治愈。
结论：据我们所知，这是首例关于嗜血杆菌菌血症的报道.D.嗜黑杆菌可能与妇科感染有关。临床医生在搜索以确定D.micraerophilus感染的重点时，应同时考虑口腔和妇科部位。
方法：我们报告一例由嗜黑D.肠表梭状芽孢杆菌,和一个47岁的女人的Eggerthellalenta，与子宫积脓有关。使用16SrRNA基因测序和基质辅助激光解吸电离飞行时间质谱鉴定了嗜微乳杆菌。使用D.micraerphilus特异性引物通过聚合酶链反应检测D.micraerophilus，并从从子宫积脓获得的引流脓液样品中分离出梭状芽孢杆菌和E.lenta。脓肿引流和2周抗生素治疗后，患者治愈。
结论：据我们所知，这是首例关于嗜血杆菌菌血症的报道.D.嗜黑杆菌可能与妇科感染有关。临床医生在搜索以确定D.micraerophilus感染的重点时，应同时考虑口腔和妇科部位。
