Abstract：
OBJECTIVE: To assess the safety and efficacy of superior laryngeal nerve block (SLNB) for microlaryngoscopic surgery (MLS).
METHODS: PubMed, Embase, Web of Science, Ovid Medline, Cochrane Library, CNKI database, VIP database, Wanfang database, and trial registry databases.
METHODS: PICOS principles were performed: adults undergoing MLS receiving SLNB compared with no-SLNB in randomized controlled trials were included. Primary outcome included the incidence of severe postoperative sore throat (POST). Secondary outcomes included perioperative mean arterial pressure (MAP) and heart rate (HR), incidence of severe postoperative cough, and anesthesia recovery time.
RESULTS: Eleven articles with 728 patients were included. Results indicated that SLNB provides lower incidence of severe POST in post-extubation 30 min (relative ratio [RR] = 0.13; 95% confidence intervals [CIs]: 0.05 ~ 0.34), 2 h (RR = 0.09; 95% CI: 0.02 ~ 0.36), 4-6 h (RR = 0.11; 95% CI: 0.03 ~ 0.41), and 24 h (RR = 0.15; 95% CI: 0.03 ~ 0.83); lower MAP (tracheal intubation: standardized mean difference [SMD] = -1.59; 95% CI: -1.69 to -0.42); suspension laryngoscope insertion: (SMD = -0.98; 95% CI: -1.49 to -0.46); tracheal extubation: (SMD = -0.78; 95% CI:-1.24 to -0.31); post-extubation 5 min: (SMD = -0.95; 95% CI: -1.41 to -0.49); lower HR (tracheal intubation: mean difference [MD] = -9.71; 95% CI: -17.16 to -2.27); suspension laryngoscope insertion: (MD = -8.64; 95% CI: -16.79 to -0.49); tracheal extubation: (MD = -10.13; 95% CI: -17.86 to -2.39); post-extubation 5 min: (MD = -13.44; 95% CI: -22.53 to -4.35); lower incidence of severe postoperative cough in post-extubation 30 min (RR = 0.18; 95% CI: 0.06 ~ 0.57) and 2 h (RR = 0.13; 95% CI: 0.02 ~ 0.69); and shorter anesthesia recovery time (MD = -5.34; 95% CI: -8.81 to -1.86) compared to controls.
CONCLUSIONS: SLNB could provide lower incidence of severe POST, more stable perioperative MAP and HR, lower incidence of severe postoperative cough, and shorter anesthesia recovery time for MLS.
METHODS: I Laryngoscope, 134:3437-3446, 2024.
METHODS: PubMed, Embase, Web of Science, Ovid Medline, Cochrane Library, CNKI database, VIP database, Wanfang database, and trial registry databases.
METHODS: PICOS principles were performed: adults undergoing MLS receiving SLNB compared with no-SLNB in randomized controlled trials were included. Primary outcome included the incidence of severe postoperative sore throat (POST). Secondary outcomes included perioperative mean arterial pressure (MAP) and heart rate (HR), incidence of severe postoperative cough, and anesthesia recovery time.
RESULTS: Eleven articles with 728 patients were included. Results indicated that SLNB provides lower incidence of severe POST in post-extubation 30 min (relative ratio [RR] = 0.13; 95% confidence intervals [CIs]: 0.05 ~ 0.34), 2 h (RR = 0.09; 95% CI: 0.02 ~ 0.36), 4-6 h (RR = 0.11; 95% CI: 0.03 ~ 0.41), and 24 h (RR = 0.15; 95% CI: 0.03 ~ 0.83); lower MAP (tracheal intubation: standardized mean difference [SMD] = -1.59; 95% CI: -1.69 to -0.42); suspension laryngoscope insertion: (SMD = -0.98; 95% CI: -1.49 to -0.46); tracheal extubation: (SMD = -0.78; 95% CI:-1.24 to -0.31); post-extubation 5 min: (SMD = -0.95; 95% CI: -1.41 to -0.49); lower HR (tracheal intubation: mean difference [MD] = -9.71; 95% CI: -17.16 to -2.27); suspension laryngoscope insertion: (MD = -8.64; 95% CI: -16.79 to -0.49); tracheal extubation: (MD = -10.13; 95% CI: -17.86 to -2.39); post-extubation 5 min: (MD = -13.44; 95% CI: -22.53 to -4.35); lower incidence of severe postoperative cough in post-extubation 30 min (RR = 0.18; 95% CI: 0.06 ~ 0.57) and 2 h (RR = 0.13; 95% CI: 0.02 ~ 0.69); and shorter anesthesia recovery time (MD = -5.34; 95% CI: -8.81 to -1.86) compared to controls.
CONCLUSIONS: SLNB could provide lower incidence of severe POST, more stable perioperative MAP and HR, lower incidence of severe postoperative cough, and shorter anesthesia recovery time for MLS.
METHODS: I Laryngoscope, 134:3437-3446, 2024.
摘要：
目的：评估喉上神经阻滞（SLNB）用于显微喉镜手术（MLS）的安全性和有效性。
方法：PubMed，Embase,WebofScience,OvidMedline,科克伦图书馆,CNKI数据库,VIP数据库,万方数据库，和审判登记数据库。
方法：执行PICOS原则：纳入接受SLNB的MLS成人与接受非SLNB的随机对照试验。主要结果包括严重术后咽喉痛（POST）的发生率。次要结果包括围手术期平均动脉压（MAP）和心率（HR），术后严重咳嗽的发生率，和麻醉恢复时间。
结果：共纳入11篇728例患者。结果表明，SLNB在拔管后30分钟内提供较低的严重POST发生率（相对比率[RR]=0.13；95％置信区间[CI]：0.05〜0.34）。2h（RR=0.09；95%CI：0.02~0.36），4-6h（RR=0.11；95%CI：0.03~0.41），和24小时；（RR=0.15；95％CI：0.03〜0.83）；较低的MAP（气管插管：至95％至2.53）；较低的MAP（气管插管时间：标准平均差[SMD]=-1.59；95％CI：-1.69至-0.42）；拔管时间0.86％=95％=95％-0.46；95％CI=95％％-95％％％％％％
结论：SLNB可以降低严重POST的发生率，围手术期MAP和HR更稳定，术后严重咳嗽的发生率较低，MLS的麻醉恢复时间较短。
方法：I喉镜，2024.
方法：PubMed，Embase,WebofScience,OvidMedline,科克伦图书馆,CNKI数据库,VIP数据库,万方数据库，和审判登记数据库。
方法：执行PICOS原则：纳入接受SLNB的MLS成人与接受非SLNB的随机对照试验。主要结果包括严重术后咽喉痛（POST）的发生率。次要结果包括围手术期平均动脉压（MAP）和心率（HR），术后严重咳嗽的发生率，和麻醉恢复时间。
结果：共纳入11篇728例患者。结果表明，SLNB在拔管后30分钟内提供较低的严重POST发生率（相对比率[RR]=0.13；95％置信区间[CI]：0.05〜0.34）。2h（RR=0.09；95%CI：0.02~0.36），4-6h（RR=0.11；95%CI：0.03~0.41），和24小时；（RR=0.15；95％CI：0.03〜0.83）；较低的MAP（气管插管：至95％至2.53）；较低的MAP（气管插管时间：标准平均差[SMD]=-1.59；95％CI：-1.69至-0.42）；拔管时间0.86％=95％=95％-0.46；95％CI=95％％-95％％％％％％
结论：SLNB可以降低严重POST的发生率，围手术期MAP和HR更稳定，术后严重咳嗽的发生率较低，MLS的麻醉恢复时间较短。
方法：I喉镜，2024.
