PDF(Pubmed)
Abstract：
In recent times, nanoparticles have experienced a significant upsurge in popularity, primarily owing to their minute size and their remarkable ability to modify physical, chemical, and biological properties. This burgeoning interest can be attributed to the expanding array of biomedical applications where nanoparticles find utility. These nanoparticles, typically ranging in size from 10 to 100 nm, exhibit diverse shapes, such as spherical, discoidal, and cylindrical configurations. These variations are not solely influenced by the manufacturing processes but are also intricately linked to interactions with surrounding stabilizing agents and initiators. Nanoparticles can be synthesized through physical or chemical methods, yet the biological approach emerges as the most sustainable and eco-friendly alternative among the three. Among the various nanoparticle types, silver nanoparticles have emerged as the most encountered and widely utilized due to their exceptional properties. What makes the synthesis of silver nanoparticles even more appealing is the application of plant-derived sources as reducing agents. This approach not only proves to be cost-effective but also significantly reduces the synthesis time. Notably, silver nanoparticles produced through plant-mediated processes have garnered considerable attention in recent years due to their notable medicinal capabilities. This comprehensive review primarily delves into the diverse medicinal attributes of silver nanoparticles synthesized using plant-mediated techniques. Encompassing antimicrobial properties, cytotoxicity, wound healing, larvicidal effects, anti-angiogenesis activity, antioxidant potential, and antiplasmodial activity, the paper extensively covers these multifaceted roles. Additionally, an endeavor is made to provide an elucidated summary of the operational mechanisms underlying the pharmacological actions of silver nanoparticles.
摘要：
最近,纳米粒子经历了一个显著的流行热潮，主要是由于它们的微小尺寸和显著的改变身体的能力，化学,和生物学特性。这种新兴的兴趣可以归因于纳米粒子在生物医学应用中应用的不断扩大。这些纳米粒子，通常尺寸范围从10到100纳米，展示不同的形状，如球形，盘状,和圆柱形配置。这些变化不仅受制造工艺的影响,而且还与与周围的稳定剂和引发剂的相互作用密切相关。纳米粒子可以通过物理或化学方法合成，然而，生物方法成为这三者中最可持续和生态友好的替代方案。在各种纳米粒子类型中，银纳米粒子已经成为最常见的和广泛使用由于其特殊的性质。使银纳米颗粒的合成更具吸引力的是植物来源作为还原剂的应用。这种方法不仅被证明是成本有效的,而且显著地减少了合成时间。值得注意的是,近年来，通过植物介导的过程产生的银纳米颗粒由于其显著的药用能力而引起了相当大的关注。这篇综合综述主要探讨了使用植物介导技术合成的银纳米颗粒的多种药用属性。包含抗菌性能，细胞毒性，伤口愈合，杀幼虫作用,抗血管生成活性，抗氧化潜力，和抗疟药活性，这篇论文广泛涵盖了这些多方面的角色。此外,努力提供对银纳米颗粒药理作用基础的运行机制的阐明摘要。
