PDF(Pubmed)
Abstract：
METHODS: Systematic Review.
OBJECTIVE: To systematically review the clinical outcomes, re-operation, and complication rates of lumbar TDR devices at mid-to long-term follow-up studies for the treatment of lumbar degenerative disc disease (DDD).
METHODS: A systematic search was conducted on PubMed, SCOPUS, and Google Scholar to identify follow-up studies that evaluated clinical outcomes of lumbar TDR in patients with DDD. The included studies met the following criteria: prospective or retrospective studies published from 2012 to 2022; a minimum of 5 years post-operative follow-up; a study sample size >10 patients; patients >18 years of age; containing clinical outcomes with Oswestry Disability Index (ODI), Visual Analog Scale (VAS), complication or reoperation rates.
RESULTS: Twenty-two studies were included with data on 2284 patients. The mean follow-up time was 8.30 years, with a mean follow-up rate of 86.91%. The study population was 54.97% female, with a mean age of 42.34 years. The mean VAS and ODI pain score improvements were 50.71 ± 6.91 and 30.39 ± 5.32 respectively. The mean clinical success and patient satisfaction rates were 74.79% ± 7.55% and 86.34% ± 5.64%, respectively. The mean complication and reoperation rates were 18.53% ± 6.33% and 13.6% ± 3.83%, respectively. There was no significant difference when comparing mid-term and long-term follow-up studies for all clinical outcomes.
CONCLUSIONS: There were significant improvements in pain reduction at last follow-up in patients with TDRs. Mid-term follow-up data on clinical outcomes, complication and reoperation rates of lumbar TDRs were maintained longer term.
OBJECTIVE: To systematically review the clinical outcomes, re-operation, and complication rates of lumbar TDR devices at mid-to long-term follow-up studies for the treatment of lumbar degenerative disc disease (DDD).
METHODS: A systematic search was conducted on PubMed, SCOPUS, and Google Scholar to identify follow-up studies that evaluated clinical outcomes of lumbar TDR in patients with DDD. The included studies met the following criteria: prospective or retrospective studies published from 2012 to 2022; a minimum of 5 years post-operative follow-up; a study sample size >10 patients; patients >18 years of age; containing clinical outcomes with Oswestry Disability Index (ODI), Visual Analog Scale (VAS), complication or reoperation rates.
RESULTS: Twenty-two studies were included with data on 2284 patients. The mean follow-up time was 8.30 years, with a mean follow-up rate of 86.91%. The study population was 54.97% female, with a mean age of 42.34 years. The mean VAS and ODI pain score improvements were 50.71 ± 6.91 and 30.39 ± 5.32 respectively. The mean clinical success and patient satisfaction rates were 74.79% ± 7.55% and 86.34% ± 5.64%, respectively. The mean complication and reoperation rates were 18.53% ± 6.33% and 13.6% ± 3.83%, respectively. There was no significant difference when comparing mid-term and long-term follow-up studies for all clinical outcomes.
CONCLUSIONS: There were significant improvements in pain reduction at last follow-up in patients with TDRs. Mid-term follow-up data on clinical outcomes, complication and reoperation rates of lumbar TDRs were maintained longer term.
摘要：
方法：系统评价。
目的：系统评价临床结果，重新操作,在治疗腰椎间盘退变性疾病（DDD）的中长期随访研究中，腰椎TDR装置的并发症发生率。
方法：在PubMed上进行了系统搜索，Scopus,和GoogleScholar，以确定评估DDD患者腰椎TDR临床结局的随访研究。纳入的研究符合以下标准：2012年至2022年发表的前瞻性或回顾性研究;术后随访至少5年;研究样本量>10例患者;年龄>18岁的患者;包含Oswestry残疾指数（ODI）的临床结果，视觉模拟量表(VAS),并发症或再手术率。
结果：22项研究纳入了2284例患者的数据。平均随访时间为8.30年,平均随访率为86.91%。研究人群为54.97%女性，平均年龄42.34岁.平均VAS和ODI疼痛评分改善分别为50.71±6.91和30.39±5.32。平均临床成功率和患者满意率分别为74.79%±7.55%和86.34%±5.64%,分别。平均并发症和再手术率分别为18.53%±6.33%和13.6%±3.83%,分别。在比较所有临床结果的中期和长期随访研究时，没有显着差异。
结论：TDR患者末次随访时疼痛减轻有显著改善。临床结果的中期随访数据，腰椎TDR的并发症和再手术率维持较长期。
目的：系统评价临床结果，重新操作,在治疗腰椎间盘退变性疾病（DDD）的中长期随访研究中，腰椎TDR装置的并发症发生率。
方法：在PubMed上进行了系统搜索，Scopus,和GoogleScholar，以确定评估DDD患者腰椎TDR临床结局的随访研究。纳入的研究符合以下标准：2012年至2022年发表的前瞻性或回顾性研究;术后随访至少5年;研究样本量>10例患者;年龄>18岁的患者;包含Oswestry残疾指数（ODI）的临床结果，视觉模拟量表(VAS),并发症或再手术率。
结果：22项研究纳入了2284例患者的数据。平均随访时间为8.30年,平均随访率为86.91%。研究人群为54.97%女性，平均年龄42.34岁.平均VAS和ODI疼痛评分改善分别为50.71±6.91和30.39±5.32。平均临床成功率和患者满意率分别为74.79%±7.55%和86.34%±5.64%,分别。平均并发症和再手术率分别为18.53%±6.33%和13.6%±3.83%,分别。在比较所有临床结果的中期和长期随访研究时，没有显着差异。
结论：TDR患者末次随访时疼痛减轻有显著改善。临床结果的中期随访数据，腰椎TDR的并发症和再手术率维持较长期。
