PDF(Pubmed)
Abstract：
We report the case of an 87-year-old woman with upper tract urothelial carcinoma at the left renal pelvis. She received stereotactic body radiotherapy of 35 Gy in five fractions for palliative treatment of hematuria that was delivered by a 1.5-T magnetic resonance (MR) imaging-guided linear accelerator. Her symptom was relieved after treatment, and posttreatment imaging revealed a complete response of the primary tumor. Thus, this case showed that stereotactic MR-guided radiotherapy could be an appealing option for inoperable patients although radiotherapy is infrequently mentioned in the current treatment guideline of upper tract urothelial carcinoma. Daily adaptive planning from MR images obtained before treatment could improve the target dose and minimize the organ at risk dose. This may lead to a decrease in radiation adverse effects including worsening renal function due to the renal pelvis tumor\'s proximity to the kidney.
摘要：
我们报告了一名87岁女性在左肾盂患有上尿路上皮癌的病例。她接受了五个部分的35Gy立体定向放射治疗，用于缓解血尿，该治疗是由1.5T磁共振（MR）成像引导的线性加速器提供的。治疗后症状缓解,治疗后影像学显示原发肿瘤完全缓解。因此，该病例表明,立体定向MR引导放射治疗对于不能手术的患者可能是一个有吸引力的选择,尽管目前上尿路尿路上皮癌治疗指南中很少提到放射治疗.治疗前获得的MR图像的每日自适应计划可以提高目标剂量并最大程度地减少危险器官的剂量。由于肾盂肿瘤靠近肾脏，这可能导致辐射不良反应减少，包括肾功能恶化。
