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Abstract：
Rickettsioses and leptospirosis are infectious diseases that are often underdiagnosed due to a lack of knowledge about their epidemiology, pathophysiology, diagnosis, management, among others.
UNASSIGNED: to characterize the seroprevalence and seroincidence of both Rickettsia and Leptospira agents and determine the risk factors for these outcomes in rural areas of Urabá, Antioquia.
UNASSIGNED: a secondary data analysis using information on Rickettsia and Leptospira exposure from a prior prospective study that explored sociocultural and ecological aspects of Rickettsia infection in rural Urabá, Colombia. A multinomial mixed logistic regression model was employed to analyze factors linked to seroprevalent cases of Rickettsia, Leptospira and both, along with descriptive analyses of seroincident cases.
UNASSIGNED: the concomitant seroprevalence against Rickettsiaand Leptospira was 9.38% [95%CI 6.08%-13.37%] (56/597). The factors associated with this seroprevalence were age (ORa= 1.02 [95%CI 1.007-1.03]), male gender (ORa= 3.06 [95%CI 1.75-5.37]), fever history (ORa= 1.71 [95%CI 1.06-2.77]) the presence of breeding pigs (ORa= 2.29 [95%CI 1.36-3.88]), peridomicile yucca crops(ORa= 2.5 [95%CI 1.1-5.62]), and deforestation practices(ORa= 1.74 [95%CI 1.06-2.87]). The concomitant seroincidence against Rickettsia and Leptospira was 1.09% (3/274) [95%CI 0.29%-4.05%], three cases were female, with a median age of 31.83 years-old (IQR 8.69-56.99). At the household level, all the seroincident cases had households built partially or totally with soil floors, wooden walls, and zinc roofs. Two seroincident cases described the presence of equines, canines, and domestic chickens in intra or peri-domicile. Finally, two cases were exposed to synanthropic rodents, and one case to tick infestation.
UNASSIGNED: there is evidence of seroprevalent and seroincident cases of seropositivity against both Rickettsia and Leptospira in rural areas of Urabá, Colombia. These findings can help improve public health surveillance systems in preventing, detecting, and attending to the different clinical cases caused by these pathogens.
UNASSIGNED: to characterize the seroprevalence and seroincidence of both Rickettsia and Leptospira agents and determine the risk factors for these outcomes in rural areas of Urabá, Antioquia.
UNASSIGNED: a secondary data analysis using information on Rickettsia and Leptospira exposure from a prior prospective study that explored sociocultural and ecological aspects of Rickettsia infection in rural Urabá, Colombia. A multinomial mixed logistic regression model was employed to analyze factors linked to seroprevalent cases of Rickettsia, Leptospira and both, along with descriptive analyses of seroincident cases.
UNASSIGNED: the concomitant seroprevalence against Rickettsiaand Leptospira was 9.38% [95%CI 6.08%-13.37%] (56/597). The factors associated with this seroprevalence were age (ORa= 1.02 [95%CI 1.007-1.03]), male gender (ORa= 3.06 [95%CI 1.75-5.37]), fever history (ORa= 1.71 [95%CI 1.06-2.77]) the presence of breeding pigs (ORa= 2.29 [95%CI 1.36-3.88]), peridomicile yucca crops(ORa= 2.5 [95%CI 1.1-5.62]), and deforestation practices(ORa= 1.74 [95%CI 1.06-2.87]). The concomitant seroincidence against Rickettsia and Leptospira was 1.09% (3/274) [95%CI 0.29%-4.05%], three cases were female, with a median age of 31.83 years-old (IQR 8.69-56.99). At the household level, all the seroincident cases had households built partially or totally with soil floors, wooden walls, and zinc roofs. Two seroincident cases described the presence of equines, canines, and domestic chickens in intra or peri-domicile. Finally, two cases were exposed to synanthropic rodents, and one case to tick infestation.
UNASSIGNED: there is evidence of seroprevalent and seroincident cases of seropositivity against both Rickettsia and Leptospira in rural areas of Urabá, Colombia. These findings can help improve public health surveillance systems in preventing, detecting, and attending to the different clinical cases caused by these pathogens.
摘要：
立克次体病和钩端螺旋体病是传染病,由于缺乏对其流行病学的了解,常被诊断不足,病理生理学,诊断,管理,在其他人中。目的：表征立克次体和钩端螺旋体的血清阳性率和血清发生率，并确定乌拉巴农村地区这些结果的危险因素，Antioquia.方法：使用先前前瞻性研究中有关立克次体和钩端螺旋体暴露的信息进行二次数据分析，该研究探索了农村乌拉巴的立克次体感染的社会文化和生态方面，哥伦比亚。采用多项混合逻辑回归模型分析与立克次体血清阳性病例相关的因素，钩端螺旋体和两者，以及血清偶发病例的描述性分析。结果：立克次体和钩端螺旋体的合并血清阳性率为9.38％[95CI6.08％-13.37％]（56/597）。与这种血清阳性率相关的因素是年龄（ORa=1.02[95CI1.007-1.03]），男性（ORa=3.06[95CI1.75-5.37]），发热史（ORa=1.71[95CI1.06-2.77]）存在种猪（ORa=2.29[95CI1.36-3.88]），丝兰果皮类作物（ORa=2.5[95CI1.1-5.62]），和森林砍伐做法(ORa=1.74[95CI1.06-2.87])。立克次体和钩端螺旋体的合并血清发生率为1.09%(3/274)[95CI0.29%-4.05%],三例是女性，年龄中位数为31.83岁（IQR8.69-56.99）。在家庭层面，所有血清学事件都有部分或全部用土壤建造的家庭，木墙,和锌屋顶。两个血清偶合病例描述了马的存在，犬科动物,和家鸡在内部或周围的住所。最后,两例暴露于同食啮齿动物，还有一个案例来感染。结论：有证据表明，在乌拉巴农村地区，针对立克次体和钩端螺旋体的血清阳性和血清阳性病例，哥伦比亚。这些发现可以帮助改善公共卫生监测系统，检测，并关注由这些病原体引起的不同临床病例。
