关键词: Anti-tuberculous therapy Ocular tuberculosis Optic neuropathy Uveitis

来  源:   DOI:10.1016/j.jctube.2023.100413   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aimed to report the clinical manifestations of presumed ocular tuberculosis (OTB) and the treatment response after anti-tuberculosis therapy (ATT) in a Chinese population.
UNASSIGNED: Clinical data, including general characteristics, ocular lesions, visual acuity at baseline, and final follow-up of patients with presumed OTB from 2006 to 2022 in two eye clinics in China, were retrospectively analyzed.
UNASSIGNED: The study included 84 eyes of 52 patients. The following ocular manifestations were observed: anterior uveitis (4.8%), posterior uveitis (34.5%), panuveitis (11.9%), retinal vasculitis (40.5%) and optic neuropathy (8.3%). After ATT, the vision improved by varying degrees in 48 eyes (57.1%), remained stable in 34 eyes (40.5%) and decreased in 2 eyes (2.4%).
UNASSIGNED: OTB is likely to be misdiagnosed as other infectious uveitis and optic neuropathy. Clinical features must be interpreted in conjunction with topical and general laboratory findings and in collaboration with other subspecialties to make a final diagnosis.
摘要:
本研究旨在报告中国人群中假定的眼结核(OTB)的临床表现和抗结核治疗(ATT)后的治疗反应。
临床数据,包括一般特征,眼部病变,基线时的视敏度,以及2006年至2022年在中国两家眼科诊所对推定OTB患者的最终随访,进行回顾性分析。
该研究包括52名患者的84只眼。观察到以下眼部表现:前葡萄膜炎(4.8%),后葡萄膜炎(34.5%),全葡萄膜炎(11.9%),视网膜血管炎(40.5%)和视神经病变(8.3%)。ATT后,48只眼睛(57.1%)的视力有不同程度的改善,34只眼(40.5%)保持稳定,2只眼(2.4%)下降。
OTB可能被误诊为其他感染性葡萄膜炎和视神经病变。临床特征必须结合局部和一般实验室发现进行解释,并与其他亚专科合作进行最终诊断。
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