PDF(Pubmed)
Abstract：
Abiotic/biotic stresses pose a major threat to agriculture and food security by impacting plant growth, productivity and quality. The discovery of extensive transcription of large RNA transcripts that do not code for proteins, termed long non-coding RNAs (lncRNAs) with sizes larger than 200 nucleotides in length, provides an important new perspective on the centrality of RNA in gene regulation. In plants, lncRNAs are widespread and fulfill multiple biological functions in stress response. In this paper, the research advances on the biological function of lncRNA in plant stress response were summarized, like as Natural Antisense Transcripts (NATs), Competing Endogenous RNAs (ceRNAs) and Chromatin Modification etc. And in plants, lncRNAs act as a key regulatory hub of several phytohormone pathways, integrating abscisic acid (ABA), jasmonate (JA), salicylic acid (SA) and redox signaling in response to many abiotic/biotic stresses. Moreover, conserved sequence motifs and structural motifs enriched within stress-responsive lncRNAs may also be responsible for the stress-responsive functions of lncRNAs, it will provide a new focus and strategy for lncRNA research. Taken together, we highlight the unique role of lncRNAs in integrating plant response to adverse environmental conditions with different aspects of plant growth and development. We envisage that an improved understanding of the mechanisms by which lncRNAs regulate plant stress response may further promote the development of unconventional approaches for breeding stress-resistant crops.
摘要：
非生物/生物胁迫通过影响植物生长对农业和粮食安全构成重大威胁。生产力和质量。不编码蛋白质的大RNA转录物的广泛转录的发现，称为长非编码RNA（lncRNAs），长度大于200个核苷酸，为RNA在基因调控中的中心地位提供了一个重要的新视角。在植物中,lncRNAs广泛存在并在应激反应中实现多种生物学功能。在本文中,综述了lncRNA在植物逆境响应中的生物学功能研究进展,如自然反义转录本(NAT)，竞争内源性RNA（ceRNA）和染色质修饰等。在植物中，lncRNAs作为几个植物激素途径的关键调控中心，整合脱落酸（ABA），茉莉酸(JA),水杨酸（SA）和氧化还原信号对许多非生物/生物胁迫的反应。此外，在应激反应性lncRNAs中富集的保守序列基序和结构基序也可能负责lncRNAs的应激反应功能，它将为lncRNA研究提供新的焦点和策略。一起来看,我们强调了lncRNAs在整合植物对不利环境条件的反应与植物生长和发育的不同方面的独特作用。我们设想，对lncRNAs调节植物应激反应的机制的更好理解可能进一步促进培育抗逆作物的非常规方法的发展。
