关键词: cardioprotection cardiovascular system mechanism of action scutellarin signal pathway

来  源:   DOI:10.3389/fphar.2023.1329969   PDF(Pubmed)

Abstract:
Cardiovascular diseases represent a significant worldwide problem, jeopardizing individuals\' physical and mental wellbeing as well as their quality of life as a result of their widespread incidence and fatality. With the aging society, the occurrence of Cardiovascular diseases is progressively rising each year. However, although drugs developed for treating Cardiovascular diseases have clear targets and proven efficacy, they still carry certain toxic and side effect risks. Therefore, finding safe, effective, and practical treatment options is crucial. Scutellarin is the primary constituent of Erigeron breviscapus (Vant.) Hand-Mazz. This article aims to establish a theoretical foundation for the creation and use of secure, productive, and logical medications for Scutellarin in curing heart-related illnesses. Additionally, the examination and analysis of the signal pathway and its associated mechanisms with regard to the employment of SCU in treating heart diseases will impart innovative resolving concepts for the treatment and prevention of Cardiovascular diseases.
摘要:
心血管疾病是一个重大的世界性问题,由于其广泛的发病率和死亡率,危及个人的身心健康以及他们的生活质量。随着社会的老龄化,心血管疾病的发病率逐年上升。然而,尽管开发的用于治疗心血管疾病的药物具有明确的靶点和证明的疗效,它们仍然具有一定的毒副作用风险。因此,找到安全,有效,和实际的治疗选择是至关重要的。灯盏花素是灯盏花(Vant。)手爵士。本文旨在为创建和使用安全,生产,以及Scutellarin治疗心脏相关疾病的合乎逻辑的药物。此外,对SCU治疗心脏病的信号通路及其相关机制的检查和分析将为心血管疾病的治疗和预防提供创新的解决理念.
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