关键词: dysbiosis endocrine disorders endocrine pathology endocrine-related cancers gut microbiome hormones microbiota

来  源:   DOI:10.3390/biomedicines12010221   PDF(Pubmed)

Abstract:
This comprehensive review article delves into the critical role of the human microbiota in the development and management of endocrine-related diseases. We explore the complex interactions between the microbiota and the endocrine system, emphasizing the implications of microbiota dysbiosis for the onset and progression of various endocrine disorders. The review aims to synthesize current knowledge, highlighting recent advancements and the potential of novel therapeutic approaches targeting microbiota-endocrine interactions. Key topics include the impact of microbiota on hormone regulation, its role in endocrine pathologies, and the promising avenues of microbiota modulation through diet, probiotics, prebiotics, and fecal microbiota transplantation. We underscore the importance of this research in advancing personalized medicine, offering insights for more tailored and effective treatments for endocrine-related diseases.
摘要:
这篇全面的综述文章探讨了人类微生物群在内分泌相关疾病的发展和管理中的关键作用。我们探索微生物群和内分泌系统之间的复杂相互作用,强调微生物群生态失调对各种内分泌疾病的发生和发展的影响。这篇综述旨在综合当前的知识,强调针对微生物群-内分泌相互作用的新治疗方法的最新进展和潜力。关键主题包括微生物群对激素调节的影响,它在内分泌病理学中的作用,以及通过饮食调节微生物群的有希望的途径,益生菌,益生元,和粪便微生物移植。我们强调了这项研究在推进个性化医疗方面的重要性,为内分泌相关疾病提供更量身定制和有效的治疗方法。
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