METHODS: In this prospective study, 189 patients with papillary thyroid cancer who underwent total thyroidectomy with central neck dissection were included. Patients were randomly allocated to one of two groups: NAF (no AF, surgery was performed without AF) and the AF group (surgery was performed with AF-Fluobeam LX system, Fluoptics, Grenoble, France).
RESULTS: The number of excised lymph nodes was significantly higher in the AF compared to the NAF group, with mean values of 21.3 ± 4.8 and 9.2 ± 4.1, respectively. Furthermore, a significantly higher number of metastatic lymph nodes were observed in the AF group. Transient hypocalcemia recorded significantly lower rates in the AF group with 4.9% compared to 16.8% in the NAF group.
CONCLUSIONS: AF use during total thyroidectomy with central neck dissection for papillary thyroid carcinoma patients, decreased the rate of iatrogenic parathyroid gland lesions, and increased the rate of lymphatic clearance.
方法:在这项前瞻性研究中,189例甲状腺乳头状癌患者行甲状腺全切除术伴中央颈清扫术。患者随机分为两组:NAF(无AF,手术是在无AF的情况下进行的)和AF组(手术是用AF-荧光LX系统进行的,Fluopics,格勒诺布尔,法国)。
结果:与NAF组相比,AF组中切除的淋巴结数量明显更高,平均值分别为21.3±4.8和9.2±4.1。此外,在AF组中观察到明显更多的转移性淋巴结.与NAF组的16.8%相比,房颤组的短暂性低钙血症发生率明显降低,为4.9%。
结论:甲状腺乳头状癌患者在甲状腺全切除术和中央颈清扫术中使用AF,降低医源性甲状旁腺病变的发生率,并提高了淋巴清除率。