PDF(Pubmed)
Abstract：
It is well known that bacterial plaque is the main etiological factor that causes the appearance of periodontal diseases and carious disease. Periodontal diseases can affect children and adolescents and are manifested in the form of gingivitis, but also the early form of chronic periodontitis as well as aggressive marginal periodontitis associated with local or general factors. Early periodontitis is frequently undiagnosed by clinicians due to a lack of knowledge of the specific symptoms. Certain systemic diseases, such as cardiovascular diseases, can create favorable conditions for the appearance and progression of severe manifestations of periodontal disease; also, recent research highlights that individuals with periodontal disease present an increased risk of developing cardiovascular diseases. Children with congenital or acquired cardiovascular diseases are at increased risk for complications resulting from the growth of microorganisms in the oral cavity, presenting a risk of infective endocarditis. The specific aim was to highlight the existing differences between the periodontal health of children with cardiovascular diseases and that of children without these diseases. The analyzed group included 124 patients, represented by children and adolescents, aged between 7 and 17 years, who were divided into four subgroups depending on the presence or absence of cardiovascular diseases and periodontal disease. A specialized clinical examination was performed for each patient, and periodontal clinical parameters were quantified (plaque index, gingival bleeding index, gingival index, community periodontal index of treatment needs) and associated with the diagnosis of general condition. Patients diagnosed with periodontal disease underwent specialized treatment and were called to a control visit 3 months after treatment. Statistical analysis showed significant differences between subgroups with much higher values of clinical parameters for patients with cardiovascular disease. Also, the response to the treatment was better in the case of patients in the control subgroup without cardiovascular diseases. The present study highlighted the interaction of three factors in the progression of periodontal diseases: subgingival microbiota, immune system response and environmental factors.
摘要：
众所周知，细菌菌斑是引起牙周疾病和龋齿疾病出现的主要病因。牙周病可以影响儿童和青少年，并以牙龈炎的形式表现出来，但也有慢性牙周炎的早期形式以及与局部或一般因素相关的侵袭性边缘性牙周炎。由于缺乏对特定症状的了解，临床医生经常无法诊断早期牙周炎。某些系统性疾病,比如心血管疾病，可以为牙周病的严重表现的出现和进展创造有利条件;最近的研究表明，患有牙周病的人患心血管疾病的风险增加。患有先天性或获得性心血管疾病的儿童由于口腔中微生物的生长而导致并发症的风险增加，有感染性心内膜炎的风险.具体目的是强调患有心血管疾病的儿童与没有这些疾病的儿童之间的牙周健康之间存在的差异。分析组包括124名患者，以儿童和青少年为代表，年龄在7至17岁之间，根据是否存在心血管疾病和牙周病，将其分为四个亚组。对每位患者进行了专门的临床检查，和牙周临床参数进行量化(菌斑指数，牙龈出血指数，牙龈指数,社区牙周指数的治疗需求）并与一般状况的诊断相关。被诊断患有牙周病的患者接受了专门的治疗，并在治疗后3个月被要求进行对照访问。统计学分析表明，对于心血管疾病患者，具有更高的临床参数值的亚组之间存在显着差异。此外，对照组无心血管疾病的患者对治疗的反应较好.本研究强调了三个因素在牙周病进展中的相互作用：牙龈下微生物群，免疫系统反应和环境因素。
