PDF(Pubmed)
Abstract：
UNASSIGNED: Holistic care is a key element in nursing care. Aiming at the heterogeneous disease of cerebral palsy, researchers focused on children with cerebral palsy who received transnasal transplantation of neural stem cells as a specific group. Based on establishing a multidisciplinary team, comprehensive care is carried out for this type of patient during the perioperative period to improve the effectiveness and safety of clinical research and increase the comfort of children.
UNASSIGNED: Between January 2018 and June 2023, 22 children with cerebral palsy underwent three transnasal transplants of neural stem cells.
UNASSIGNED: No adverse reactions related to immune rejection were observed in the 22 children during hospitalization and follow-up. All children tolerated the treatment well, and the treatment was superior. One child developed nausea and vomiting after sedation; three had a small amount of bleeding of nasal mucosa after transplantation. Two children had a low fever (≤38.5°C), and one had a change in the type and frequency of complex partial seizures. Moreover, 3 children experienced patch shedding within 4 h of patch implantation into the nasal cavity.
UNASSIGNED: The project team adopted nasal stem cell transplantation technology. Based on the characteristics of transnasal transplantation of neural stem cells in the treatment of neurological diseases in children, a comprehensive and novel holistic care plan is proposed. It is of great significance to guide caregivers of children to complete proper care, further improve the safety and effectiveness of treatment, and reduce the occurrence of complications.
UNASSIGNED: Between January 2018 and June 2023, 22 children with cerebral palsy underwent three transnasal transplants of neural stem cells.
UNASSIGNED: No adverse reactions related to immune rejection were observed in the 22 children during hospitalization and follow-up. All children tolerated the treatment well, and the treatment was superior. One child developed nausea and vomiting after sedation; three had a small amount of bleeding of nasal mucosa after transplantation. Two children had a low fever (≤38.5°C), and one had a change in the type and frequency of complex partial seizures. Moreover, 3 children experienced patch shedding within 4 h of patch implantation into the nasal cavity.
UNASSIGNED: The project team adopted nasal stem cell transplantation technology. Based on the characteristics of transnasal transplantation of neural stem cells in the treatment of neurological diseases in children, a comprehensive and novel holistic care plan is proposed. It is of great significance to guide caregivers of children to complete proper care, further improve the safety and effectiveness of treatment, and reduce the occurrence of complications.
摘要：
■整体护理是护理中的关键要素。针对脑瘫的异质性疾病,研究人员重点研究了接受神经干细胞经鼻移植的脑瘫儿童作为一个特定群体。在建立多学科团队的基础上，围手术期对该类患者进行综合护理,提高临床研究的有效性和安全性,增加患儿的舒适度。
■在2018年1月至2023年6月之间，22名脑瘫儿童接受了三次经鼻神经干细胞移植。
■22例患儿在住院和随访期间均未观察到与免疫排斥相关的不良反应。所有的孩子都能很好地接受治疗，治疗效果优越。1例患儿镇静后出现恶心呕吐；3例移植后鼻粘膜少量出血。两个孩子低烧（≤38.5°C），其中一人的复杂部分性癫痫发作的类型和频率发生了变化。此外，3名儿童在贴片植入鼻腔后4小时内出现贴片脱落。
■项目组采用鼻干细胞移植技术。基于神经干细胞经鼻移植治疗儿童神经系统疾病的特点,提出了一项全面而新颖的整体护理计划。引导儿童照顾者完成适当的照顾具有重要意义，进一步提高治疗的安全性和有效性，减少并发症的发生。
■在2018年1月至2023年6月之间，22名脑瘫儿童接受了三次经鼻神经干细胞移植。
■22例患儿在住院和随访期间均未观察到与免疫排斥相关的不良反应。所有的孩子都能很好地接受治疗，治疗效果优越。1例患儿镇静后出现恶心呕吐；3例移植后鼻粘膜少量出血。两个孩子低烧（≤38.5°C），其中一人的复杂部分性癫痫发作的类型和频率发生了变化。此外，3名儿童在贴片植入鼻腔后4小时内出现贴片脱落。
■项目组采用鼻干细胞移植技术。基于神经干细胞经鼻移植治疗儿童神经系统疾病的特点,提出了一项全面而新颖的整体护理计划。引导儿童照顾者完成适当的照顾具有重要意义，进一步提高治疗的安全性和有效性，减少并发症的发生。
