PDF(Pubmed)
Abstract：
A 14-year-old female domestic short-haired cat with a diagnosed diabetes mellitus and acromegaly was presented for lethargy and dysorexia. On clinical presentation, the patient showed hyperglycemia, hyperthermia, dull mentation, and dehydration. With the suspicion of an inflammatory or infectious complication of diabetes, she was hospitalized with constant rate infusion of insulin, and empirical ampicillin sulbactam was started. Blood culture revealed positivity for Yersinia pseudotuberculosis and the septic picture was confirmed by blood analysis, with leukocytosis, neutrophilia, and an increased serum amyloid A concentration. The isolated Y. pseudotuberculosis strain showed susceptibility to every antimicrobial tested. During the second day of hospitalization, the onset of hypoglycemia and hypotension was treated with norepinephrine and glucose in fluid therapy. The cat recovered well and was discharged with insulin and amoxicillin-clavulanate. This is the first case of septicemia associated with Y. pseudotuberculosis in a cat, suspected of developing the infection after contact with natural reservoirs such as rodents or birds. This route of transmission should be highlighted especially in relation to the zoonotic potential of the bacteria.
摘要：
一只14岁的雌性家养短毛猫被诊断患有糖尿病和肢端肥大症，因嗜睡和功能障碍而出现。关于临床表现，病人表现出高血糖,热疗,沉闷的心理状态，和脱水。由于怀疑糖尿病的炎症或感染性并发症，她因恒速注射胰岛素住院,开始使用经验性氨苄西林舒巴坦。血培养显示假结核耶尔森氏菌阳性，通过血液分析证实了脓毒症的情况。白细胞增多症，嗜中性粒细胞增多症,血清淀粉样蛋白A浓度升高。分离的Y.假结核菌株对所测试的每种抗微生物剂都具有敏感性。在住院的第二天，低血糖和低血压的发作在液体治疗中接受去甲肾上腺素和葡萄糖治疗.猫恢复良好，并与胰岛素和阿莫西林-克拉维酸一起出院。这是猫中首例与Y.假结核相关的败血症，怀疑与啮齿动物或鸟类等天然水库接触后感染。这种传播途径尤其应与细菌的人畜共患潜力有关。
