PDF(Pubmed)
Abstract：
The objective of the study was to describe the frequency of acute myocardial injury (AMI) assessed by high-sensitivity cardiac troponin I (hs-cTnI) levels and to determine the possible initial risk factors (related to the characteristics of the patient, the disease, and the initial management) in a population of adult patients with early sepsis (within the first 72 h of diagnosis) in a single tertiary hospital center in western Mexico. For the inferential statistics, the proportions of the categorical dichotomous variables were compared using the chi-square test. In all analyses, p values less than 0.05 with a 95% confidence interval were considered significant. We included a total of 64 patients diagnosed with early sepsis, of whom 46 presented elevated hs-cTnI and were classified as having AMI. In our study, the frequency of AMI in patients with early sepsis was 71.87%, and no significant differences were found in all of the characteristics of patients with early sepsis with and without AMI, nor was any significant association found with any of the variables analyzed. In the population of western Mexico, the frequency of AMI in patients with early sepsis, assessed by hs-cTnI levels, is high and similar to that reported in other populations worldwide.
摘要：
该研究的目的是描述通过高敏心肌肌钙蛋白I（hs-cTnI）水平评估的急性心肌损伤（AMI）的频率，并确定可能的初始危险因素（与患者的特征，疾病,和初始管理）在墨西哥西部一家三级医院中心的早期败血症成年患者（在诊断的前72小时内）中。对于推理统计，使用卡方检验比较分类二分变量的比例。在所有分析中,具有95%置信区间的小于0.05的p值被认为是显著的。我们纳入了64例诊断为早期脓毒症的患者，其中46人的hs-cTnI升高，被归类为患有AMI。在我们的研究中,早期脓毒症患者发生AMI的频率为71.87%,早期脓毒症患者与无AMI患者的所有特征均无显著差异,也未发现与所分析的任何变量有任何显著关联.在墨西哥西部的人口中，早期脓毒症患者的AMI频率，按hs-cTnI水平评估，很高，与全球其他人群的报道相似。
