Abstract:
Previous studies on the efficacy of trans-sutural distraction osteogenesis (TSDO) to treat midface hypoplasia caused by cleft lip and palate (CLP) have mainly focused on objective measurements while ignoring the subjective feelings of patients. This study aimed to analyse the changes in and correlation between computed tomography (CT) measurements and FACE-Q scores in patients who underwent TSDO by performing a comprehensive evaluation from both objective and subjective perspectives. This retrospective study included 25 patients with an average age of 10.7 years who had midface hypoplasia caused by CLP and underwent TSDO between August 2018 and December 2022. The average follow-up time was 18.8 ± 7.7 months. Facial morphology and CT measurements, including A-CR, N-A⊥HR, the SNA angle and the L-ZA, indicated significant improvements in midface concavity (all p < 0.0001). All FACE-Q scores (except for facial function) exhibited a significant increase. The ΔA-CR, ΔN-A⊥HR, and ΔSNA angle were strongly correlated with specific aspects of the FACE-Q-Appearance items, including the ΔFACE-Q-Appearance of the cheeks (all p < 0.0001), the ΔFACE-Q-Appearance of the face (all p < 0.0001), the ΔFACE-Q-Appearance of the jaws (all p < 0.01), the ΔSatisfaction with decision (all p < 0.0001) and the ΔSatisfaction with outcome (all p < 0.001). However, the ΔA-CR, ΔN-A⊥HR, and ΔSNA were weakly correlated with other FACE-Q-Health-related quality of life and function items. These findings suggest that both CT findings and FACE-Q scores have their own emphases and advantages. It is necessary to establish an integrated curative effect evaluation model that combines FACE-Q scores with CT measurements to evaluate both the physical health and psychological status of patients.
摘要:
以往关于经缝牵张成骨(TSDO)治疗唇腭裂(CLP)引起的中面发育不全的疗效研究主要集中在客观测量上,而忽略了患者的主观感受。这项研究旨在通过从客观和主观角度进行综合评估,分析接受TSDO的患者的计算机断层扫描(CT)测量值与FACE-Q评分之间的变化和相关性。这项回顾性研究包括25名平均年龄为10.7岁的患者,这些患者在2018年8月至2022年12月期间患有由CLP引起的面部发育不全并接受TSDO。平均随访时间为18.8±7.7个月。面部形态学和CT测量,包括A-CR,N-AHLHR,SNA角度和L-ZA,表明中表面凹度有显著改善(所有p<0.0001)。所有FACE-Q评分(面部功能除外)均表现出显着增加。ΔA-CR,ΔN-AHLHR,和ΔSNA角度与FACE-Q外观项目的特定方面密切相关,包括脸颊的ΔFACE-Q-外观(所有p<0.0001),面部的ΔFACE-Q-外观(所有p<0.0001),颌骨的ΔFACE-Q-外观(所有p<0.01),Δ对决策的满意度(所有p<0.0001)和Δ对结果的满意度(所有p<0.001)。然而,ΔA-CR,ΔN-AHLHR,和ΔSNA与其他FACE-Q-健康相关的生活质量和功能项目弱相关。这些发现表明,CT检查结果和FACE-Q评分都有自己的重点和优势。有必要建立FACE-Q评分与CT测量相结合的综合疗效评估模型,以评估患者的身体健康状况和心理状况。