Abstract：
Seborrheic keratosis(SK) is a very common skin tumor which is mostly frequently observed in the trunck, head, neck. SK in the auricle is rare and this condition should be excluded the possibility of malignancy by pathologic diagnosis. We report a case of 66-year-old man who presented with a brownish, papillomatous, verrucous mass in the auricle for the past seven years, which began to growing faster during the previous year. Dermoscopy and histopathological examination were performed and the patient was diagnosed with SK. He was treated with the carbon dioxide(CO2) laser and aminolevulinate photodynamic therapy (ALA-PDT). The CO2 laser was used for the removal of the thick hypertrophic lesions and to enhance the transdermal absorption efficiency of ALA. A 20% ALA cream(118 mg/cm2) was applied to his lesion and sealed for 3 h without light, followed by irradiation with 630-nm LED light (96 J/cm2, 80 mw/cm2). We use fluorescent diagnosis with aminolevulinic acid to define the tumor margins at the first session of ALA-PDT. After 4 sessions of ALA-PDT, the lesion was completely removed and did not recur. Therefore, we consider that ALA-PDT combined with CO2 laser is a safe and effective choice for the treatment of seborrheic keratosis in the auricle.
摘要：
脂溢性角化病（SK）是一种非常常见的皮肤肿瘤，通常在trunck中观察到。头部,脖子。耳廓中的SK很少见，应通过病理诊断排除恶性肿瘤的可能性。我们报告了一例66岁的男子，他的皮肤呈褐色，乳头状瘤，在过去的七年里，耳廓有疣，在前一年开始增长更快。进行皮肤镜检查和组织病理学检查，患者被诊断为SK。他接受了二氧化碳（CO2）激光和氨基evulate光动力疗法（ALA-PDT）治疗。CO2激光用于去除厚厚的肥大性病变并提高ALA的透皮吸收效率。将20％ALA乳膏（118mg/cm2）涂在他的病变上，并在没有光照的情况下密封3小时。然后用630nm的LED光(96J/cm2,80mw/cm2)照射。我们使用氨基酮戊酸的荧光诊断来定义ALA-PDT第一届会议的肿瘤边缘。在ALA-PDT的4次会议之后，病变已完全切除且未复发.因此,我们认为ALA-PDT联合CO2激光治疗耳廓脂溢性角化病是一种安全有效的选择。
