Abstract：
Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus infection and is a benign hyperplastic lesion of the genital and perianal areas. The principle of its treatment is to remove the visible warts as much as possible and to prevent recurrence. Traditional treatment methods of condyloma acuminatum, such as CO2 laser, liquid nitrogen freezing, surgery, and topical medications, can remove warts. However, these methods have disadvantages such as pain, high recurrence rates, long treatment cycles, and scarring. Aminolevulinic acid/photodynamic therapy (ALA-PDT), a safe and effective method, has been widely used to treat condyloma acuminatum in recent years. Condyloma acuminatum occurs relatively rarely in elderly patients, in whom treatment is difficult owing to poorer physiological function. We successfully treated an 87-year-old patient with a giant condyloma acuminatum of the glans penis using six sessions of ALA-PDT at 7-day intervals and obtained satisfactory results. No recurrence was observed during a 6-month follow-up. Therefore, ALA-PDT is worth popularizing in clinical practice.
摘要：
尖锐湿疣是由人乳头瘤病毒感染引起的常见性传播疾病，是生殖器和肛周区域的良性增生性病变。其治疗原则是尽可能去除可见的疣并防止复发。尖锐湿疣的传统治疗方法，如CO2激光器，液氮冷冻,手术,和局部用药，可以去除疣。然而,这些方法有缺点，如疼痛，高复发率,治疗周期长,和疤痕。氨基乙酰丙酸/光动力疗法(ALA-PDT),一种安全有效的方法，近年来尖锐湿疣已被广泛用于治疗。尖锐湿疣在老年患者中相对少见，由于生理功能较差，治疗困难。我们以7天的间隔使用6次ALA-PDT成功治疗了一名87岁的巨大龟头尖锐湿疣患者，并获得了令人满意的结果。在6个月的随访中没有观察到复发。因此,ALA-PDT值得临床推广。
