PDF(Pubmed)
Abstract：
OBJECTIVE: To investigate the difference of medial rectus (MR) and lateral rectus (LR) between acute acquired concomitant esotropia (AACE) and the healthy controls (HCs) detected by magnetic resonance imaging (MRI).
METHODS: A case-control study. Eighteen subjects with AACE and eighteen HCs were enrolled. MRI scanning data were conducted in target-controlled central gaze with a 3-Tesla magnetic resonance scanner. Extraocular muscles (EOMs) were scanned in contiguous image planes 2-mm thick spanning the EOM origins to the globe equator. To form posterior partial volumes (PPVs), the LR and MR cross-sections in the image planes 8, 10, 12, and 14 mm posterior to the globe were summed and multiplied by the 2-mm slice thickness. The data were classified according to the right eye, left eye, dominant eye, and non-dominant eye, and the differences in mean cross-sectional area, maximum cross-sectional area, and PPVs of the MR and LR muscle in the AACE group and HCs group were compared under the above classifications respectively.
RESULTS: There were no significant differences between the two groups of demographic characteristics. The mean cross-sectional area of the LR muscle was significantly greater in the AACE group than that in the HCs group in the non-dominant eyes (P=0.028). The maximum cross-sectional area of the LR muscle both in the dominant and non-dominant eye of the AACE group was significantly greater than the HCs group (P=0.009, P=0.016). For the dominant eye, the PPVs of the LR muscle were significantly greater in the AACE than that in the HCs group (P=0.013), but not in the MR muscle (P=0.698).
CONCLUSIONS: The size and volume of muscles dominant eyes of AACE subjects change significantly to overcome binocular diplopia. The LR muscle become larger to compensate for the enhanced convergence in the AACE.
METHODS: A case-control study. Eighteen subjects with AACE and eighteen HCs were enrolled. MRI scanning data were conducted in target-controlled central gaze with a 3-Tesla magnetic resonance scanner. Extraocular muscles (EOMs) were scanned in contiguous image planes 2-mm thick spanning the EOM origins to the globe equator. To form posterior partial volumes (PPVs), the LR and MR cross-sections in the image planes 8, 10, 12, and 14 mm posterior to the globe were summed and multiplied by the 2-mm slice thickness. The data were classified according to the right eye, left eye, dominant eye, and non-dominant eye, and the differences in mean cross-sectional area, maximum cross-sectional area, and PPVs of the MR and LR muscle in the AACE group and HCs group were compared under the above classifications respectively.
RESULTS: There were no significant differences between the two groups of demographic characteristics. The mean cross-sectional area of the LR muscle was significantly greater in the AACE group than that in the HCs group in the non-dominant eyes (P=0.028). The maximum cross-sectional area of the LR muscle both in the dominant and non-dominant eye of the AACE group was significantly greater than the HCs group (P=0.009, P=0.016). For the dominant eye, the PPVs of the LR muscle were significantly greater in the AACE than that in the HCs group (P=0.013), but not in the MR muscle (P=0.698).
CONCLUSIONS: The size and volume of muscles dominant eyes of AACE subjects change significantly to overcome binocular diplopia. The LR muscle become larger to compensate for the enhanced convergence in the AACE.
摘要：
目的：探讨磁共振成像（MRI）检测急性获得性共同性内斜视（AACE）与健康对照组（HCs）内直肌（MR）和外直肌（LR）的差异。
方法：病例对照研究。招募了18名AACE和18名HC患者。使用3特斯拉磁共振扫描仪在目标控制的中央凝视中进行MRI扫描数据。在2毫米厚的连续图像平面中扫描眼外肌（EOM），该平面跨越EOM起点到地球赤道。为了形成后部分体积(PPV)，将眼球后方8,10,12和14mm的图像平面中的LR和MR横截面求和并乘以2mm的切片厚度。数据是根据右眼分类的,左眼,优势眼,和非优势眼，和平均横截面积的差异，最大横截面积,在上述分类下，分别比较AACE组和HC组的MR和LR肌肉的PPV。
结果：两组人口统计学特征之间没有显着差异。在非优势眼中，AACE组LR肌肉的平均横截面积明显大于HCs组（P=0.028）。AACE组的优势眼和非优势眼中LR肌肉的最大横截面积显著大于HC组（P=0.009，P=0.016）。对于优势眼来说，AACE组LR肌PPV显著大于HCs组(P=0.013),但不是在MR肌肉（P=0.698）。
结论：在克服双眼复视的情况下，AACE受试者以肌肉为主眼的大小和体积发生显著变化。LR肌肉变大,以补偿AACE中增强的会聚。
方法：病例对照研究。招募了18名AACE和18名HC患者。使用3特斯拉磁共振扫描仪在目标控制的中央凝视中进行MRI扫描数据。在2毫米厚的连续图像平面中扫描眼外肌（EOM），该平面跨越EOM起点到地球赤道。为了形成后部分体积(PPV)，将眼球后方8,10,12和14mm的图像平面中的LR和MR横截面求和并乘以2mm的切片厚度。数据是根据右眼分类的,左眼,优势眼,和非优势眼，和平均横截面积的差异，最大横截面积,在上述分类下，分别比较AACE组和HC组的MR和LR肌肉的PPV。
结果：两组人口统计学特征之间没有显着差异。在非优势眼中，AACE组LR肌肉的平均横截面积明显大于HCs组（P=0.028）。AACE组的优势眼和非优势眼中LR肌肉的最大横截面积显著大于HC组（P=0.009，P=0.016）。对于优势眼来说，AACE组LR肌PPV显著大于HCs组(P=0.013),但不是在MR肌肉（P=0.698）。
结论：在克服双眼复视的情况下，AACE受试者以肌肉为主眼的大小和体积发生显著变化。LR肌肉变大,以补偿AACE中增强的会聚。
