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Abstract：
Introduction: Head and neck cancers (HNCs) present a significant global health burden, especially in India, where oral cavity cancers, notably affecting the tongue, are prevalent. A substantial portion of global HNCs (57.5%) is concentrated in Asia, India contributing with 30%. Despite advancements, challenges persist due to HNCs\' invasive nature and metastatic potential. This study aims to explore the link between HNCs and ocular manifestations. Methods: A cross-sectional study was conducted at Bangalore Medical College and Research Institute involving 47 patients with diagnosed HNCs and ocular complaints. Clinical evaluations encompassed visual acuity, anterior and posterior segment examinations, and specialized investigations when necessary. Results: A diverse range of malignancies were observed, with SCC maxilla and xeroderma pigmentosa, each accounting for 10.63% of cases. Ocular examinations unveiled visual acuity challenges, anterior segment findings like masses, exotropia, pigmented lesions, and varied fundus abnormalities. The anterior segment findings encompassed masses often accompanied by protrusion or relative afferent pupillary defect (RAPD). Additionally, exotropia, pigmented lesions, and other conditions were observed. Fundus examination revealed a spectrum of findings, including media haziness (10.63%), lack of view (17.02%), and pale discs (6.38%). Treatment plans were diverse, including excision biopsies (42.55%), exenteration procedures, Mitomycin-C applications, and referrals for chemotherapy and radiotherapy. Conclusion: The present study underscores the significance of ophthalmological assessment and investigations in patients with diagnosed HNCs, emphasizing the value of early detection and intervention. Abbreviations: HNC = Head and Neck Cancer, OCT = Optical Coherence Tomography, WNL = Within Normal Limits, SCC = Squamous Cell Carcinoma, MRI = Magnetic Resonance Imaging, CT = Computed Tomography, RAPD = Relative Afferent Pupillary Defect, XP = Xeroderma Pigmentosa.
摘要：
简介：头颈癌(HNCs)带来了巨大的全球健康负担，尤其是在印度,口腔癌，特别是影响舌头，是普遍的。全球跨国公司的很大一部分(57.5%)集中在亚洲，印度贡献30%。尽管取得了进步，由于HNC的侵袭性和转移潜力，挑战依然存在。本研究旨在探讨HNC与眼部表现之间的联系。方法：在班加罗尔医学院和研究所进行了一项横断面研究，涉及47例确诊为HNC和眼部不适的患者。临床评估包括视力，前段和后段检查，必要时进行专门调查。结果：观察到各种恶性肿瘤，患有SCC上颌骨和色素性干皮病，各占病例的10.63%。眼部检查揭示了视力挑战，眼前段发现像肿块，外斜视,色素性病变,和各种眼底异常。眼前段发现包括肿块，通常伴有突出或相对传入瞳孔缺损（RAPD）。此外,外斜视,色素性病变,并观察到其他条件。眼底检查揭示了一系列发现，包括媒体混浊(10.63%)，缺乏观点(17.02%)，和浅盘(6.38%)。治疗计划多种多样，包括切除活检（42.55%），exenterationprocedures,丝裂霉素-C的应用，以及化疗和放疗的转诊。结论：本研究强调了诊断为HNC的患者的眼科评估和调查的意义。强调早期发现和干预的价值。缩写：HNC=头颈部癌，OCT=光学相干断层扫描，WNL=在正常范围内，SCC=鳞状细胞癌，MRI=磁共振成像,CT=计算机断层扫描,RAPD=相对传入瞳孔缺损，XP=色素性干皮病。
