Abstract:
Necropsy is the postmortem examination of an animal\'s body. Experiments on laboratory animals are performed to gather scientific data relevant to basic and, even more often, translational research, mainly in the field of translational medicine. A necropsy conducted on laboratory animals subjected to experimental research provides an opportunity to exhaustively explore pathological processes that took place during life. In order to achieve that goal, procedures of biomaterial collection should be performed timely, bearing in mind the inevitable process of postmortem tissue decay, and precisely, to avoid mechanical tissue damage.In this chapter, procedures of collecting organs and tissue in a way that ensures the preservation of the organ structure, tissue organization, morphological characteristics of cells, and last but not least, intracellular protein and nucleic acid content and chromosome organization are going to be described step by step.
摘要:
尸检是对动物身体的尸检。对实验动物进行实验,以收集与基本和相关的科学数据,甚至更多的时候,翻译研究,主要在转化医学领域。对进行实验研究的实验动物进行尸检提供了详尽探索生命中发生的病理过程的机会。为了实现这个目标,生物材料收集程序应及时执行,记住死后组织腐烂的不可避免的过程,准确地说,以避免机械性组织损伤。在这一章中,以确保器官结构保存的方式收集器官和组织的程序,组织组织,细胞的形态特征,最后但并非最不重要的,细胞内蛋白质和核酸含量以及染色体组织将逐步描述。