PDF(Pubmed)
Abstract：
UNASSIGNED: Chronic ankle instability (CAI) has been considered a neurophysiological disease, having as symptoms dysfunction in somatosensory and motor system excitability. Rehabilitation has been considered an effective treatment for CAI. However, few studies have explored the effects of rehabilitation on neuroplasticity in the CAI population.
UNASSIGNED: The purpose of this study was to investigate the effects of rehabilitation on cortical activities for postural control in CAI patients and to find the correlation between the change in cortical activities and patient-reported outcomes (PROs).
UNASSIGNED: Thirteen participants with CAI (6 female, 7 male, age = 33.8 ± 7.7 years, BMI = 24.7 ± 4.9 kg/m2) received a home exercise program for about 40 min per day, four days per week and six weeks, including ankle range-of-motion exercise, muscle strengthening, and balance activities. Cortical activation, PROs and Y-balance test outcomes were assessed and compared before and after rehabilitation. Cortical activation was detected via Functional near-infrared spectroscopy (fNIRS) while the participants performed single-leg stance tasks.
UNASSIGNED: The participants had better PROs and Y balance test outcomes after rehabilitation. Greater cortical activation was observed in the primary somatosensory cortex (S1, d = 0.66, p = 0.035), the superior temporal gyrus (STG, d = 1.06, p = 0.002) and the middle temporal gyrus (MTG, d = 0.66, p = 0.035) in CAI patients after rehabilitation. Moreover, significant positive correlations were observed between the recovery of ankle symptoms and the change of cortical activation in S1 (r = 0.74, p = 0.005) and STG (r = 0.72, p = 0.007) respectively.
UNASSIGNED: The current study reveals that six weeks of rehabilitation can cause greater cortical activation in S1, STG and MTG. This increase in cortical activation suggested a better ability to perceive somatosensory stimuli and may have a compensatory role in function improvement.
UNASSIGNED: The purpose of this study was to investigate the effects of rehabilitation on cortical activities for postural control in CAI patients and to find the correlation between the change in cortical activities and patient-reported outcomes (PROs).
UNASSIGNED: Thirteen participants with CAI (6 female, 7 male, age = 33.8 ± 7.7 years, BMI = 24.7 ± 4.9 kg/m2) received a home exercise program for about 40 min per day, four days per week and six weeks, including ankle range-of-motion exercise, muscle strengthening, and balance activities. Cortical activation, PROs and Y-balance test outcomes were assessed and compared before and after rehabilitation. Cortical activation was detected via Functional near-infrared spectroscopy (fNIRS) while the participants performed single-leg stance tasks.
UNASSIGNED: The participants had better PROs and Y balance test outcomes after rehabilitation. Greater cortical activation was observed in the primary somatosensory cortex (S1, d = 0.66, p = 0.035), the superior temporal gyrus (STG, d = 1.06, p = 0.002) and the middle temporal gyrus (MTG, d = 0.66, p = 0.035) in CAI patients after rehabilitation. Moreover, significant positive correlations were observed between the recovery of ankle symptoms and the change of cortical activation in S1 (r = 0.74, p = 0.005) and STG (r = 0.72, p = 0.007) respectively.
UNASSIGNED: The current study reveals that six weeks of rehabilitation can cause greater cortical activation in S1, STG and MTG. This increase in cortical activation suggested a better ability to perceive somatosensory stimuli and may have a compensatory role in function improvement.
摘要：
■慢性踝关节不稳（CAI）被认为是一种神经生理学疾病，具有体感和运动系统兴奋性功能障碍的症状。康复已被认为是CAI的有效治疗方法。然而,很少有研究探讨康复对CAI人群神经可塑性的影响。
■本研究的目的是研究康复对CAI患者姿势控制的皮质活动的影响，并发现皮质活动的变化与患者报告的结果（PRO）之间的相关性。
■13名CAI参与者（6名女性，7男,年龄=33.8±7.7岁，BMI=24.7±4.9kg/m2）每天接受约40分钟的家庭锻炼计划，每周四天和六周，包括踝关节活动范围锻炼,肌肉加强，平衡活动。皮质活化,评估和比较康复前后的PRO和Y平衡测试结果。通过功能近红外光谱（fNIRS）检测到皮质激活，而参与者执行单腿站立任务。
■参与者在康复后有更好的PRO和Y平衡测试结果。在初级体感皮层中观察到更大的皮层激活（S1，d=0.66，p=0.035），颞上回(STG，d=1.06，p=0.002）和颞中回（MTG，康复后CAI患者的d=0.66，p=0.035）。此外，踝关节症状恢复与S1(r=0.74,p=0.005)和STG(r=0.72,p=0.007)皮质活化变化呈正相关。
■目前的研究表明，6周的康复可以导致S1、STG和MTG的皮质激活。皮质激活的增加表明感知体感刺激的能力更好，并且可能在功能改善中具有代偿作用。
■本研究的目的是研究康复对CAI患者姿势控制的皮质活动的影响，并发现皮质活动的变化与患者报告的结果（PRO）之间的相关性。
■13名CAI参与者（6名女性，7男,年龄=33.8±7.7岁，BMI=24.7±4.9kg/m2）每天接受约40分钟的家庭锻炼计划，每周四天和六周，包括踝关节活动范围锻炼,肌肉加强，平衡活动。皮质活化,评估和比较康复前后的PRO和Y平衡测试结果。通过功能近红外光谱（fNIRS）检测到皮质激活，而参与者执行单腿站立任务。
■参与者在康复后有更好的PRO和Y平衡测试结果。在初级体感皮层中观察到更大的皮层激活（S1，d=0.66，p=0.035），颞上回(STG，d=1.06，p=0.002）和颞中回（MTG，康复后CAI患者的d=0.66，p=0.035）。此外，踝关节症状恢复与S1(r=0.74,p=0.005)和STG(r=0.72,p=0.007)皮质活化变化呈正相关。
■目前的研究表明，6周的康复可以导致S1、STG和MTG的皮质激活。皮质激活的增加表明感知体感刺激的能力更好，并且可能在功能改善中具有代偿作用。
