METHODS: This cross-sectional study was conducted on 3709 Japanese patients with NAFLD. The primary endpoint was the prevalence of MASLD in patients with NAFLD. The difference between the original waist circumference criteria (>94 cm for men and >80 cm for women) and the Japanese metabolic syndrome criteria (≥85 cm for men and ≥90 cm for women) for concordance between NAFLD and MASLD was also investigated.
RESULTS: According to the original criteria, the prevalence of MASLD in patients with NAFLD was 96.7%. Similarly, according to the Japanese waist circumference criteria, 96.2% of patients with NAFLD could be reclassified as those with MASLD. The concordance rate was significantly higher in the original criteria than in the Japanese criteria (p = 0.02).
CONCLUSIONS: NAFLD could be considered MASLD using the original MASLD criteria in the Japanese population, and insights from NAFLD research could be applied to MASLD.
方法:这项横断面研究是对3709名日本NAFLD患者进行的。主要终点是NAFLD患者中MASLD的患病率。还调查了原始腰围标准(男性>94厘米,女性>80厘米)和日本代谢综合征标准(男性≥85厘米,女性≥90厘米)之间NAFLD和MASLD一致性的差异。
结果:根据原始标准,NAFLD患者中MASLD的患病率为96.7%.同样,根据日本的腰围标准,96.2%的NAFLD患者可以重新分类为MASLD患者。原始标准的一致率显着高于日本标准(p=0.02)。
结论:NAFLD可以被认为是使用日本人口的原始MASLD标准,NAFLD研究的见解可以应用于MASLD。