PDF(Pubmed)
Abstract：
UNASSIGNED: Although numerous studies have indicated the utility of waist-to-height ratio (WHtR) in early screening for individuals with adverse cardiometabolic health, there is controversy on using WHtR as a one-size-fits-all approach, including in older adults.
UNASSIGNED: Our study aims to identify the pooled diagnostic accuracy of WHtR in screening for metabolic syndrome (MetS) and its components among older adults.
UNASSIGNED: A systematic review of observational studies was performed using 4 databases. A diagnostic meta-analysis with a random effects model was conducted, and the pooled area under the summary receiver operating characteristic curve, sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio (dOR) of each outcome compared with WHtR, body mass index (BMI), and waist circumference (WC) were calculated, with sex-stratified analysis.
UNASSIGNED: A total of 17 studies with 74,520 participants were included. As reflected by the dOR, WHtR (7.65; 95% CI: 6.00, 9.75) performed better than BMI (5.17; 95% CI: 4.75, 5.62) and WC (5.77; 95% CI: 4.60, 7.25) in screening for MetS among older adults and was potentially better among males. For hyperglycemia, hypertension, and dyslipidemia, the performances of WHtR, BMI, and WC were comparable.
UNASSIGNED: More studies focusing on older adults are still needed to determine the cutoff values of WHtR to screen for MetS.The search strategy was registered in PROSPERO as CRD42022350379.
UNASSIGNED: Our study aims to identify the pooled diagnostic accuracy of WHtR in screening for metabolic syndrome (MetS) and its components among older adults.
UNASSIGNED: A systematic review of observational studies was performed using 4 databases. A diagnostic meta-analysis with a random effects model was conducted, and the pooled area under the summary receiver operating characteristic curve, sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio (dOR) of each outcome compared with WHtR, body mass index (BMI), and waist circumference (WC) were calculated, with sex-stratified analysis.
UNASSIGNED: A total of 17 studies with 74,520 participants were included. As reflected by the dOR, WHtR (7.65; 95% CI: 6.00, 9.75) performed better than BMI (5.17; 95% CI: 4.75, 5.62) and WC (5.77; 95% CI: 4.60, 7.25) in screening for MetS among older adults and was potentially better among males. For hyperglycemia, hypertension, and dyslipidemia, the performances of WHtR, BMI, and WC were comparable.
UNASSIGNED: More studies focusing on older adults are still needed to determine the cutoff values of WHtR to screen for MetS.The search strategy was registered in PROSPERO as CRD42022350379.
摘要：
■尽管许多研究表明，腰围与身高比（WHtR）在心脏代谢健康不良患者的早期筛查中具有实用性，关于使用WHTR作为一刀切的方法存在争议，包括老年人。
■我们的研究旨在确定WHtR在筛查老年人代谢综合征（MetS）及其组成部分中的汇总诊断准确性。
■使用4个数据库对观察性研究进行了系统评价。使用随机效应模型进行了诊断荟萃分析，和汇总接受者工作特性曲线下的合并面积，灵敏度,特异性，正负似然比，与WHtR相比，每个结果的诊断优势比（dOR），体重指数（BMI），计算腰围(WC)，进行性别分层分析。
■共17项研究，包括74,520名参与者。正如DOR所反映的那样，WHtR(7.65;95%CI:6.00,9.75)在老年人的MetS筛查中表现优于BMI(5.17;95%CI:4.75,5.62)和WC(5.77;95%CI:4.60,7.25)，在男性中可能更好。对于高血糖，高血压,和血脂异常，WHTR的表演，BMI,和WC具有可比性。
■仍需要更多针对老年人的研究来确定WHtR的截止值，以筛选MetS。搜索策略在PROSPERO中注册为CRD42022350379。
■我们的研究旨在确定WHtR在筛查老年人代谢综合征（MetS）及其组成部分中的汇总诊断准确性。
■使用4个数据库对观察性研究进行了系统评价。使用随机效应模型进行了诊断荟萃分析，和汇总接受者工作特性曲线下的合并面积，灵敏度,特异性，正负似然比，与WHtR相比，每个结果的诊断优势比（dOR），体重指数（BMI），计算腰围(WC)，进行性别分层分析。
■共17项研究，包括74,520名参与者。正如DOR所反映的那样，WHtR(7.65;95%CI:6.00,9.75)在老年人的MetS筛查中表现优于BMI(5.17;95%CI:4.75,5.62)和WC(5.77;95%CI:4.60,7.25)，在男性中可能更好。对于高血糖，高血压,和血脂异常，WHTR的表演，BMI,和WC具有可比性。
■仍需要更多针对老年人的研究来确定WHtR的截止值，以筛选MetS。搜索策略在PROSPERO中注册为CRD42022350379。
