PDF(Pubmed)
Abstract：
This study is a retrospective review of data from patients who were incidentally diagnosed with endometrial stromal sarcoma after a routine hysterectomy for uterine fibroid at the Department of Gynaecologic Oncology in a tertiary care hospital. The Institutional Review Board (IRB) gave its clearance for this study before it was carried out. Informed written consent was obtained from all patients. In our case series, the three patients presented with complaints of menorrhagia, lower abdominal pain, intermenstrual bleeding, and acute retention of urine. After the patients underwent a clinical examination and radiological scan, the diagnosis of fibroids was made. They underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy. Histology revealed low-grade endometrial stromal sarcoma (LGESS). The patients were observed for adjuvant therapy. The patients had a follow-up period of 18-24 months. In LGESS, which is rare, prompt management is of utmost importance, because the tumour\'s stage is the most significant predictor of the prognosis. As there are no clear indications to suggest the presence of LGESS prior to the histopathology of the specimen, it is necessary to analyze the data of patients who are diagnosed with LGESS, in order to investigate and manage the condition more appropriately. After myomectomy for a suspected leiomyoma, there is a 0.2% chance of the result showing endometrial stromal sarcoma.
摘要：
这项研究是对三级医院妇科肿瘤科常规子宫肌瘤切除术后偶然诊断为子宫内膜间质肉瘤的患者数据的回顾性回顾。机构审查委员会（IRB）在进行这项研究之前批准了这项研究。从所有患者获得知情的书面同意。在我们的案例系列中，三名病人主诉月经过多,下腹部疼痛,经期出血,和急性尿潴留。患者接受临床检查和放射扫描后，诊断为肌瘤。他们接受了全腹子宫切除术和双侧附件卵巢切除术。组织学显示低度子宫内膜间质肉瘤（LGESS）。观察患者的辅助治疗情况。患者的随访期为18-24个月。在LGESS,这是罕见的，迅速的管理至关重要，因为肿瘤的分期是预后的最重要预测因素。由于在标本的组织病理学检查之前没有明确的迹象表明存在LGESS，有必要分析诊断为LGESS的患者的数据，以便更适当地调查和管理病情。疑似平滑肌瘤的子宫肌瘤切除术后，结果显示子宫内膜间质肉瘤的几率为0.2%。
