PDF(Pubmed)
Abstract：
Bartter syndrome is a genetic condition characterized by autosomal recessive inheritance, resulting in impaired salt reabsorption and clinical manifestations such as low/normal blood pressure and extracellular fluid volume depletion. Multiple abnormalities of the electrolytes, including decreased potassium as well as chloride levels and, in some instances, hypomagnesemia, are its defining features. Metabolic alkalosis, hypokalaemia, hypocalcemia, and hypomagnesemia, together with adequate renal function, are all components of the Bartter-like syndrome. It is associated with certain antibiotics and antineoplastic drugs. We report a case of traumatic brain injury with pneumothorax who was on treatment on colistin and presented with metabolic disturbance.
摘要：
Bartter综合征是一种以常染色体隐性遗传为特征的遗传病,导致盐重吸收受损和临床表现，如低/正常血压和细胞外液容量耗尽。电解质的多种异常，包括钾和氯化物水平下降，在某些情况下,低镁血症,是它的定义特征。代谢性碱中毒,低钾血症,低钙血症,和低镁血症，加上足够的肾功能，都是Bartter样综合征的组成部分.它与某些抗生素和抗肿瘤药物有关。我们报告了一例患有气胸的创伤性脑损伤，正在接受粘菌素治疗并出现代谢紊乱。
