关键词: Congenital Egypt Liver diseases Orphan Rare

Mesh : Humans Egypt / epidemiology Liver Diseases / epidemiology diagnosis Rare Diseases / epidemiology diagnosis

来  源:   DOI:10.1016/j.ajg.2023.12.002

Abstract:
Illnesses that afflict a tiny number of individuals are referred to as rare diseases (RDs), sometimes called orphan diseases. The local healthcare systems are constantly under financial, psychological, and medical strain due to low incidence rates, unusual presentations, flawed diagnostic standards, and a lack of treatment alternatives for these RDs. The effective management of the once widely spread viral hepatitis B and C has altered the spectrum of liver diseases in Egypt during the last several years. The detection of uncommon disorders such as autoimmune, cholestatic, and hereditary liver diseases has also been made easier by the increasing knowledge and greater accessibility of specific laboratory testing. Finally, despite Egypt\'s large population, there are more uncommon liver disorders than previously thought. This review article discusses the clinical and epidemiological characteristics of a few uncommon liver disorders and the information currently accessible concerning these illnesses in Egypt.
摘要:
困扰少数人的疾病被称为罕见疾病(RD),有时被称为孤儿病。当地的医疗系统一直处于财政状况,心理,和由于低发病率引起的医疗应变,不寻常的介绍,有缺陷的诊断标准,以及这些RD缺乏治疗替代方案。在过去的几年中,曾经广泛传播的病毒性乙型和丙型肝炎的有效管理改变了埃及的肝病谱。检测不常见的疾病,如自身免疫性疾病,胆汁淤积,和遗传性肝病也已经变得更容易通过不断增加的知识和更多的可及性的特定实验室检测。最后,尽管埃及人口众多,有更多的罕见的肝脏疾病比以前认为。这篇综述文章讨论了一些罕见的肝脏疾病的临床和流行病学特征以及埃及目前可获得的有关这些疾病的信息。
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