METHODS: Eleven NLE patients were included in the study, and all patients were evaluated clinically with RCM. We also evaluated RCM images from 11 eczema patients as controls.
RESULTS: Some major key diagnostic features of NLE can be observed by RCM: an enlarged honeycomb pattern (9/11, 81.8%), round-to-oval cyst-like structures were present (6/11, 54.5%), the normal ring-like structures were totally or partially obliterated (11/11, 100%) at the level of the dermo-epidermal junction, medium refractivity collagen fibers that were disorganized (10/11, 90.9%), numerous high refractivity round cells (11/11, 100%) in the dermis.
CONCLUSIONS: RCM allows the visualization of major key diagnostic features of NLE and serves as a complementary diagnostic tool for NLE.
方法:将9例NLE患者纳入研究,所有患者均采用RCM进行临床评估.我们还评估了9例湿疹患者作为对照的RCM图像。
结果:RCM可以观察到NLE的一些主要关键诊断特征,扩大的蜂窝图案(7/9,78%),存在圆形至卵圆形囊肿样结构(6/9,67%),正常的环状结构在真皮-表皮交界处完全或部分消失(9/9,100%),中等折射率杂乱无章的粗纤维材料(8/9,89%),大量高折射率圆形细胞(9/9,100%)在真皮。
结论:RCM可以可视化NLE的主要关键诊断特征,并作为NLE的补充诊断工具。