关键词: anaplastic ependymoma optic nerve stereotactic radiosurgery

来  源:   DOI:10.3171/CASE23686   PDF(Pubmed)

Abstract:
BACKGROUND: Ependymomas rarely disseminate to other central nervous system areas distant from the original site. Stereotactic radiosurgery (SRS) provides high control rates for recurring ependymomas. The treatment of optic nerve tumors carries high morbidity, but SRS is an acceptable option to manage these cases to reduce risks.
METHODS: The authors report the case of a 31-year-old male with a cervical spinal ependymoma who had a disseminated pattern of recurrence including the optic nerve after initial resection of the cervical lesion. The optic nerve tumor was treated with SRS, and the authors discuss the technical aspects of the treatment and its outcomes. At the last follow-up, the optic nerve tumor was controlled with SRS, and visual function was preserved.
CONCLUSIONS: High-grade ependymomas such as the one in the presented case can have unpredictable patterns of recurrence. SRS provides excellent control of the distant recurring ependymoma with a low complication profile given the location of the tumor in this case.
摘要:
背景:室管膜瘤很少传播到远离原始部位的其他中枢神经系统区域。立体定向放射外科(SRS)为复发性室管膜瘤提供了高控制率。视神经肿瘤的治疗具有很高的发病率,但SRS是管理这些病例以降低风险的可接受选择。
方法:作者报告了一例31岁男性颈脊髓室管膜瘤,在初次切除宫颈病变后出现包括视神经在内的扩散型复发。视神经肿瘤用SRS治疗,作者讨论了治疗的技术方面及其结果。在最后一次随访中,用SRS控制了视神经肿瘤,视觉功能得以保留。
结论:本病例中的高级别室管膜瘤可能具有不可预测的复发模式。在这种情况下,考虑到肿瘤的位置,SRS可以很好地控制远处复发的室管膜瘤,并发症发生率低。
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