PDF(Pubmed)
Abstract：
Malaria is a major public health problem in developing countries. The burden of malaria in fragile and conflict-affected states (FCAS) is increasing year by year. Moreover, the population living in FCAS is often the most vulnerable and at high risk of malaria due to factors, such as deteriorating healthcare system, mass relocations, and reduced resilience to shocks. Therefore, this scoping review aims to map the interventions that are conducted at the FCAS on malaria prevention among the general population. In addition, this review can help policy-makers and international health bodies, providing a comprehensive overview that can lead to more targeted, effective, and context-specific interventions. Databases, such as PubMed, EBSCO-CINAHL, Web of Science, ProQuest, and Cochrane Central Register of Controlled Trials, were searched using specified search terms. A total of 3601 studies were retrieved from the search. After screening, 62 studies were included in the synthesis that met the eligibility criteria. Narrative analysis of the findings was done. The results revealed that in fragile countries, interventions for children below 5 years of age included IPTi, TDA, and ACT. In conflicted countries, interventions for children below 5 years of age included TDA, LLINs, SMC, drug trials, and vaccination. Similar interventions were reported for other age groups and populations. Despite ongoing conflicts, malaria interventions have been maintained in these countries, but a persistent high burden of malaria remains. To achieve the goals of malaria elimination, the results of the review highlight the need for continued research and evaluation of malaria control interventions to assess their effectiveness and impact. Strengthening health systems, building partnerships, utilizing digital health technologies, and conducting context-specific research are recommended to improve healthcare access and reduce the burden of malaria in FCAS.
摘要：
疟疾是发展中国家的主要公共卫生问题。脆弱和受冲突影响国家的疟疾负担逐年增加。此外，生活在FCAS中的人口通常是最脆弱的，并且由于因素而处于疟疾的高风险中，例如恶化的医疗保健系统，大量重新定位，并降低了对冲击的抵抗力。因此,本范围审查旨在绘制FCAS在一般人群中开展的疟疾预防干预措施.此外,这项审查可以帮助决策者和国际卫生机构，提供一个全面的概述，可以导致更有针对性的，有效,以及针对具体情况的干预措施。数据库,比如PubMed,EBSCO-CINAHL,WebofScience,ProQuest,和Cochrane中央控制试验登记册，已使用指定的搜索词进行搜索。从搜索中检索到总共3601项研究。筛选后,62项符合资格标准的研究被纳入综合。对研究结果进行了叙事分析。结果显示，在脆弱的国家，对5岁以下儿童的干预措施包括IPTi，TDA,和ACT。在冲突国家,对5岁以下儿童的干预措施包括TDA，LLINs,SMC,药物试验,和疫苗接种。据报道，其他年龄组和人群也有类似的干预措施。尽管冲突不断,这些国家一直保持着疟疾干预措施，但是疟疾的持续高负担仍然存在。为了实现消除疟疾的目标，审查结果强调需要继续研究和评估疟疾控制干预措施，以评估其有效性和影响。加强卫生系统，建立伙伴关系,利用数字健康技术，并建议开展针对具体情况的研究，以改善FCAS的医疗保健服务并减轻疟疾负担。
