PDF(Pubmed)
Abstract：
Amyloidosis is an infiltrative disease where amyloid fibrils get deposited in the organs like kidney, liver and spleen. Amyloid deposition in the kidneys classically meant deposition in the glomeruli and mesangium until 2008 when interstitial amyloid deposits were isolated and named as` Leukocyte cell-derived chemotaxin 2-associated amyloidosis. It is a progressive disease which clinically manifests as slowly progressive renal dysfunction and/or proteinuria. Our case 34 year old renal transplant recipient underwent graft biopsy post transplantation which revealed interstitial LECT-2 amyloid deposits. Unfortunately, he developed page kidney post biopsy which was managed conservatively with percutaneous drainage.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12291-022-01072-6.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12291-022-01072-6.
摘要：
淀粉样变是一种浸润性疾病，淀粉样纤维沉积在肾脏等器官中，肝脏和脾脏。肾脏中的淀粉样蛋白沉积通常是指肾小球和肾小球系膜中的沉积，直到2008年才分离出间质淀粉样蛋白沉积并命名为“白细胞衍生的趋化素2相关的淀粉样变性”。它是临床上表现为缓慢进行性肾功能障碍和/或蛋白尿的进行性疾病。我们的病例34岁的肾移植受者在移植后接受了移植物活检，发现间质LECT-2淀粉样蛋白沉积。不幸的是,他在活检后出现了页面肾脏，并通过经皮引流进行了保守治疗。
■在线版本包含补充材料，可在10.1007/s12291-022-01072-6获得。
■在线版本包含补充材料，可在10.1007/s12291-022-01072-6获得。
