关键词: cigarette smoking intracerebral hemorrhage sildenafil stroke

Mesh : Male Humans Middle Aged Sildenafil Citrate / adverse effects Cigarette Smoking Cerebral Hemorrhage / chemically induced diagnostic imaging Erectile Dysfunction Risk Factors

来  源:   DOI:10.2147/VHRM.S443995   PDF(Pubmed)

Abstract:
UNASSIGNED: Intracerebral hemorrhage (ICH) is a serious condition characterized by bleeding within the brain tissue. Although the use of sildenafil, a vasodilator agent for erectile dysfunction, has been associated with rare cases of ICH, the combination of sildenafil usage and smoking as risk factors for ICH has not yet been reported. This case report describes the occurrence of ICH in a patient with a history of both sildenafil usage and heavy smoking.
UNASSIGNED: A 53-year-old male, with a history of smoking and regular sildenafil use, was brought to the emergency department due to loss of consciousness with right-side weakness, he initially experienced with nausea, vomiting and dizziness after taking sildenafil 100mg tablet once. The Glasgow Coma Score (GCS) was 10 with side hemiparesis. Non-contrast CT revealed left thalamic acute hemorrhage with ventricular extension. Furthermore, a head CT angiography ruled out any vascular anomalies after that the patient was admitted to the intensive care unit (ICU) for conservative management. After three days on clinical and neurological improvement, the patient was transferred to the inpatient ward for further management, monitoring and physiotherapy. On day 6, the patient was discharged and planned for flow up.
UNASSIGNED: This rare case highlights the need for further research and awareness regarding the potential risks associated with the combination of sildenafil and heavy smoking. Healthcare professionals should carefully evaluate the individual risk factors of patients, educate them about potential complications, and consider alternative treatments if necessary. Additionally, patients should be encouraged to quit smoking and adopt a healthy lifestyle to minimize the risk of cerebrovascular events.
摘要:
脑出血(ICH)是一种严重的疾病,其特征是脑组织内出血。虽然使用西地那非,一种治疗勃起功能障碍的血管扩张剂,与罕见的ICH病例有关,西地那非使用和吸烟作为ICH危险因素的组合尚未有报道.该病例报告描述了同时使用西地那非和大量吸烟的患者中ICH的发生。
一名53岁的男性,有吸烟史,经常使用西地那非,由于右侧无力意识丧失而被带到急诊室,他最初经历了恶心,服用西地那非100mg片剂后呕吐和头晕。格拉斯哥昏迷评分(GCS)为10,伴有偏瘫。CT增强显示左丘脑急性出血伴心室扩张。此外,头部CT血管造影排除了患者入住重症监护病房(ICU)进行保守治疗后的任何血管异常.在临床和神经系统改善三天后,病人被转移到住院病房接受进一步治疗,监测和物理治疗。在第6天,患者出院并计划上流。
这一罕见病例突出了需要进一步研究和认识与西地那非和大量吸烟的组合相关的潜在风险。医疗保健专业人员应仔细评估患者的个人风险因素,教育他们潜在的并发症,并在必要时考虑替代疗法。此外,应鼓励患者戒烟并采取健康的生活方式,以降低脑血管事件的风险.
公众号