UNASSIGNED: This study is a prospective analysis of patients following DJS ablation. A total of 155 patients from our institution were enrolled in this study between January 2023 and May 2023. Bladder urine was collected in a sterile container prior to stent removal for bacteriological exam. The removed stents were divided into three parts: top (Renal), middle (Ureteral), and bottom (Bladder); 3 cm pieces from each part were taken and placed in a sterile test tube for bacteriological investigation.
UNASSIGNED: The mean age of patients with positive stent culture was 61.17±12.82 versus 55.94±10.32 when stent culture is negative, which is statistically significant P=0.016. Diabetes and bacteriuria are both correlated with DJS contamination with P<0.001 in the two cases. The mean duration of the use of DJS in patients with colonized stent culture is 6.45±2.98 months versus 4.06±2.20 months for the other patients; the difference is statistically significant P<0.001. The most commonly isolated pathogens on stents were Gram-negative bacilli (53.2%), dominated by Enterobacteriaceae in 19 cases (55.2%).
UNASSIGNED: Indwelling time is the only unanimous factor of stent colonization in literature, so we recommend using DJS only if necessary and to remove it as soon as possible.
■本研究是对DJS消融术后患者的前瞻性分析。在2023年1月至2023年5月期间,共有155名来自我们机构的患者参加了这项研究。在支架移除之前将膀胱尿液收集在无菌容器中用于细菌学检查。取出的支架分为三部分:顶部(肾),中部(输尿管),和底部(膀胱);从每个部分取3厘米的碎片,并放置在无菌试管中进行细菌学研究。
■支架培养阳性患者的平均年龄为61.17±12.82,而支架培养阴性患者的平均年龄为55.94±10.32,具有统计学意义P=0.016。2例糖尿病和菌尿均与DJS污染相关,P<0.001。定植支架培养患者使用DJS的平均时间为6.45±2.98个月,其他患者为4.06±2.20个月,差异有统计学意义P<0.001。支架上最常见的病原菌是革兰氏阴性杆菌(53.2%),以肠杆菌科为主的19例(55.2%)。
■留置时间是文献中支架定植的唯一一致因素,所以我们建议只在必要时使用DJS,并尽快删除它。