Abstract:
Gluteal tendinopathy (GT) is common and can be debilitating and challenging to manage. A lack of condition specific and appropriate outcome measures compromise evidence synthesis for treatment and limits clinical guideline development. Our objective was to develop a core outcome measurement set for GT (COS-GT). Participants were patients with GT and expert health professionals (HPs). A scoping review identified measures used in GT research, which were mapped to the nine International Scientific Tendinopathy Symposium Consensus core domains, and included in two surveys of HPs. The first survey identified the feasible and true measures for each domain. The second survey refined the list which a patient focus group then considered. Meeting online, HPs reached consensus (agreement ≥70%) on the most appropriate COS-GT measures. 34 HPs and seven patients were recruited. 57 measures were mapped to the nine core domains. Six measures did not proceed past survey one. Of those that progressed, none had adequate clinimetric properties for a COS-GT. Thus, participants decided on interim measures: the global rating of change, pain at night, time to pain onset with single limb stance, pain with stair walking, pain self-efficacy and hip abduction strength. HP participants additionally recommended that pain over the last week, the European Quality of Life-5 dimensions-5 levels and the Victorian Institute of Sport Assessment-Gluteal be considered in clinical trials, as they currently provide best easures of the relevant tendinopathy domains. In conclusion this interim COS-GT should guide outcome measure selection in clinical practice and future research trials in patients with GT.
摘要:
臀腱病(GT)很常见,可能使人衰弱且具有挑战性。缺乏特定条件和适当的结果指标会影响治疗的证据综合,并限制了临床指南的制定。我们的目标是开发GT(COS-GT)的核心结果测量集。参与者是GT患者和专业健康专家(HP)。范围审查确定了GT研究中使用的措施,被映射到九个国际科学肌腱病研讨会共识核心领域,并包括在两次对惠普的调查中。第一次调查确定了每个领域的可行和真实措施。第二项调查完善了患者焦点小组随后考虑的列表。在线会议,惠普就最合适的COS-GT措施达成共识(协议≥70%)。招募了34名HP和7名患者。57项措施被映射到九个核心域。六项措施没有在调查一之前进行。在那些进步的人中,COS-GT没有足够的临床特性。因此,与会者决定了临时措施:全球变化评级,晚上疼痛,单肢姿势疼痛发作的时间,楼梯行走时疼痛,疼痛自我效能感和髋关节外展力量。惠普参与者还建议上周疼痛,在临床试验中考虑欧洲生活质量-5维度-5水平和维多利亚运动评估研究所-黄体,因为它们目前提供了相关肌腱病领域的最佳治疗方法。总之,该临时COS-GT应指导临床实践和未来GT患者研究试验中的结局指标选择。