关键词: Gynecologic cancer Gynecologic conditions Pregnancy Probiotics Vaginal health Women's health

Mesh : Pregnancy Female Humans Women's Health Vagina / microbiology Vaginosis, Bacterial / prevention & control Probiotics / therapeutic use Lactobacillus Polycystic Ovary Syndrome

来  源:   DOI:10.1016/j.tjog.2023.09.018

Abstract:
Probiotics, live microorganisms that confer health benefits to the host when administered in adequate amounts, have gained considerable attention for their potential role in maintaining women\'s health. This overview summarizes key clinical findings on the beneficial effects of probiotics in various aspects of women\'s health. Probiotics, particularly Lactobacillus species, contribute to vaginal health by promoting a balanced vaginal microbiome to prevent infections and maintain an acidic environment. In gynecologic conditions, probiotics show potential in preventing and managing bacterial vaginosis, vulvovaginal candidiasis, and sexually transmitted infections. Probiotic supplementation has also been associated with improvements in metabolic parameters and menstrual irregularities in polycystic ovary syndrome patients. During pregnancy, probiotics may be helpful in reducing the risk of gestational diabetes, maternal group B streptococcal colonization, obstetric anemia, and postpartum mastitis. In recent years, the potential role of probiotics in the prevention and management of gynecologic cancer has gained attention. Further research is needed to better understand the specific mechanisms and determine the optimal Lactobacillus strains and dosages regimens for gynecologic cancer prevention and therapy. In conclusion, probiotics offer a non-invasive and cost-effective approach to support women\'s health and prevent obstetric and gynecologic complications.
摘要:
益生菌,当给予足够的量时,赋予宿主健康益处的活微生物,因其在维护女性健康方面的潜在作用而获得了相当多的关注。本综述总结了益生菌在女性健康各个方面的有益作用的关键临床发现。益生菌,特别是乳酸菌,通过促进平衡的阴道微生物组来预防感染和维持酸性环境,从而促进阴道健康。在妇科疾病中,益生菌显示出预防和管理细菌性阴道病的潜力,外阴阴道念珠菌病,和性传播感染。益生菌补充剂还与多囊卵巢综合征患者的代谢参数和月经不调的改善有关。在怀孕期间,益生菌可能有助于降低妊娠期糖尿病的风险,产妇B组链球菌定植,产科贫血,产后乳腺炎.近年来,益生菌在妇科癌症预防和治疗中的潜在作用已引起人们的关注。需要进一步研究以更好地了解具体机制并确定用于妇科癌症预防和治疗的最佳乳杆菌菌株和剂量方案。总之,益生菌提供了一种非侵入性和具有成本效益的方法来支持妇女的健康和预防产科和妇科并发症。
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