PDF(Pubmed)
Abstract：
BACKGROUND: Highly virulent multidrug-resistant Klebsiella pneumoniae (KP) is becoming more and more common in clinical practice, especially the rise of carbapenem-resistant KP in clinical practice, resulting in the emergence of KP liver abscess in Ningxia, China. For the prognosis of liver abscess patients, it is particularly important to identify the types of pathogens and identify antibiotics that are sensitive to the pathogens.
METHODS: A 73-year-old man from China presents to our hospital with abdominal pain, jaundice and fever. Patients have no obvious cause of abdominal pain, abdominal distension, and abdominal pain is persistent. Abdominal examination showed hepatomegaly, no tenderness 2 cm from the right costal margin, abdominal distension and other general examinations did not have obvious abnormalities. He had no history of hypertension and diabetes, ERCP was performed for cholangiocarcinoma 1 year before the current visit, and no significant complications occurred.
METHODS: His initial diagnosis was obstructive cholangitis, and computed tomographic images and liver drainage fluid bacterial culture and genetic polymerase chain reaction tests later determined that the patient had KP liver abscess.
METHODS: Drainage by liver catheter and antibiotic treatment for 7 weeks.
RESULTS: The patient liver abscess is basically gone.
UNASSIGNED: It is particularly important to optimize the diagnosis of liver abscess pathogens for timely and effective treatment of patients.
METHODS: A 73-year-old man from China presents to our hospital with abdominal pain, jaundice and fever. Patients have no obvious cause of abdominal pain, abdominal distension, and abdominal pain is persistent. Abdominal examination showed hepatomegaly, no tenderness 2 cm from the right costal margin, abdominal distension and other general examinations did not have obvious abnormalities. He had no history of hypertension and diabetes, ERCP was performed for cholangiocarcinoma 1 year before the current visit, and no significant complications occurred.
METHODS: His initial diagnosis was obstructive cholangitis, and computed tomographic images and liver drainage fluid bacterial culture and genetic polymerase chain reaction tests later determined that the patient had KP liver abscess.
METHODS: Drainage by liver catheter and antibiotic treatment for 7 weeks.
RESULTS: The patient liver abscess is basically gone.
UNASSIGNED: It is particularly important to optimize the diagnosis of liver abscess pathogens for timely and effective treatment of patients.
摘要：
背景：高毒力多药耐药肺炎克雷伯菌（KP）在临床实践中越来越普遍，尤其是碳青霉烯类耐药KP在临床实践中的兴起，导致宁夏KP肝脓肿的出现，中国。对于肝脓肿患者的预后，识别病原体的类型和识别对病原体敏感的抗生素尤为重要。
方法：一位来自中国的73岁男子因腹痛来我院就诊，黄疸和发烧。患者没有明显的腹痛原因，腹胀,腹痛持续。腹部检查显示肝肿大,距右肋缘2厘米无压痛，腹胀等一般检查无明显异常。他没有高血压和糖尿病病史，在本次就诊前1年对胆管癌进行ERCP，无明显并发症发生。
方法：他最初的诊断是梗阻性胆管炎，计算机断层扫描图像和肝引流液细菌培养和遗传聚合酶链反应测试后来确定患者患有KP肝脓肿。
方法：肝导管引流和抗生素治疗7周。
结果：患者肝脓肿基本消失。
■优化肝脓肿病原体的诊断对于及时有效地治疗患者尤为重要。
方法：一位来自中国的73岁男子因腹痛来我院就诊，黄疸和发烧。患者没有明显的腹痛原因，腹胀,腹痛持续。腹部检查显示肝肿大,距右肋缘2厘米无压痛，腹胀等一般检查无明显异常。他没有高血压和糖尿病病史，在本次就诊前1年对胆管癌进行ERCP，无明显并发症发生。
方法：他最初的诊断是梗阻性胆管炎，计算机断层扫描图像和肝引流液细菌培养和遗传聚合酶链反应测试后来确定患者患有KP肝脓肿。
方法：肝导管引流和抗生素治疗7周。
结果：患者肝脓肿基本消失。
■优化肝脓肿病原体的诊断对于及时有效地治疗患者尤为重要。
