关键词: Breast cancer lymphedema anastomosis lipectomy lymph nodes (LNs) lymphedema/surgery surgical

来  源:   DOI:10.21037/atm-23-292   PDF(Pubmed)

Abstract:
UNASSIGNED: Breast cancer-related lymphedema (BCRL) represents a colossal burden in terms of health and patient-reported outcomes. Surgical management plays a prominent role in the psychological and physical well-being of women suffering from BCRL. Therefore, we performed a narrative review of the current surgical management of BCRL and analyzed the postoperative results.
UNASSIGNED: A literature search was conducted across PubMed MEDLINE, Scopus, and Web of Science from database inception through January 2, 2023. We included English-written studies evaluating postoperative outcomes of lymphatic surgery for the management of BCRL.
UNASSIGNED: The surgical management of lymphedema can be classified into two approaches: (I) physiologic procedures and (II) debulking or ablative procedures. While ablative procedures are intended to lessen the symptomatic burden of lymphedema via the removal of pathological tissues, physiologic procedures are performed to restore the abnormal lymphatic flow by creating bypasses into the venous or lymphatic circulation, or by creating new lymphatic connections by means of lymphangiogenesis. Physiologic procedures generate better outcomes in the early stages of lymphedema as there is some residual physiologic flow and vessels are less fibrotic, while ablative procedures are regarded to be the best alternative in very advanced lymphedema stages. A combination of physiologic and ablative procedures provides more comprehensive surgical management to BCRL.
UNASSIGNED: Lymphedema is a common complication of breast cancer treatment with an extensive incidence range. Postoperative outcomes of the surgical management of BCRL are heterogeneous despite most studies indicating favorable results after lymphatic surgery.
摘要:
乳腺癌相关淋巴水肿(BCRL)在健康和患者报告的结果方面是巨大的负担。手术管理在患有BCRL的妇女的心理和身体健康中起着重要作用。因此,我们对目前BCRL的手术治疗进行了叙述性回顾,并分析了术后结果.
在PubMedMEDLINE进行了文献检索,Scopus,和WebofScience从数据库开始到2023年1月2日。我们纳入了评估淋巴手术治疗BCRL术后结果的英文书面研究。
淋巴水肿的外科治疗可分为两种方法:(I)生理程序和(II)减积或消融程序。虽然消融手术旨在通过切除病理组织来减轻淋巴水肿的症状负担,生理程序是通过创建旁路进入静脉或淋巴循环来恢复异常淋巴流动,或者通过淋巴管生成创造新的淋巴连接。生理程序在淋巴水肿的早期阶段产生更好的结果,因为有一些残留的生理流和血管纤维化较少,而消融手术被认为是非常晚期淋巴水肿的最佳选择。生理和消融程序的组合为BCRL提供了更全面的手术管理。
淋巴水肿是乳腺癌治疗的常见并发症,发病率范围广泛。尽管大多数研究表明淋巴手术后取得了良好的结果,但BCRL手术治疗的术后结果却不相同。
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