PDF(Pubmed)
Abstract：
BACKGROUND: Cervical cancer has been considered as one of the most common cancers in women (15-44 years) globally, but the advent of the human papilloma virus (HPV) vaccine has raised the anticipation that eradication of cervical carcinoma might be achieved in the near future as several prophylactic cervical carcinoma vaccines have already been currently licensed in various countries. Countries should devise strategies, practices and policies to attain and sustain higher levels of HPV immunization coverage as still 68% countries have introduced HPV vaccine in their national immunization programs even after 17 years following the licensure of the first prophylactic HPV vaccine.
METHODS: A comprehensive literature analysis was conducted using various databases and search engines, to include the most relevant research articles and data available and critically discussed the operational gaps that need to be answered to achieve adequate coverage of HPV vaccination.
RESULTS: The present review highlights the existing HPV vaccination strategies, unmet needs and challenges needed to be addressed for proper implementation framework as well as the collaborations required to achieve decent vaccination coverage. Well-coordinated vaccination strategy with focus on adolescent girls and if possible, boys can lead to dramatic impact on disease reduction around the world.
METHODS: A comprehensive literature analysis was conducted using various databases and search engines, to include the most relevant research articles and data available and critically discussed the operational gaps that need to be answered to achieve adequate coverage of HPV vaccination.
RESULTS: The present review highlights the existing HPV vaccination strategies, unmet needs and challenges needed to be addressed for proper implementation framework as well as the collaborations required to achieve decent vaccination coverage. Well-coordinated vaccination strategy with focus on adolescent girls and if possible, boys can lead to dramatic impact on disease reduction around the world.
摘要：
背景：宫颈癌被认为是全球女性（15-44岁）最常见的癌症之一，但是人乳头瘤病毒(HPV)疫苗的出现提高了人们对宫颈癌根除可能在不久的将来实现的预期,因为目前已有几种预防性宫颈癌疫苗在多个国家获得许可.各国应该制定战略，实践和政策，以实现和维持更高水平的HPV免疫覆盖率，因为即使在第一个预防性HPV疫苗获得许可后17年，仍有68％的国家在其国家免疫计划中引入了HPV疫苗。
方法：使用各种数据库和搜索引擎进行了全面的文献分析，纳入现有的最相关的研究文章和数据，并批判性地讨论了实现HPV疫苗接种的足够覆盖率所需解决的操作差距。
结果：本综述重点介绍了现有的HPV疫苗接种策略，需要解决未满足的需求和挑战，以实现适当的实施框架以及实现体面的疫苗接种覆盖率所需的合作。协调良好的疫苗接种策略，重点是少女，如果可能的话，男孩会对世界各地的疾病减少产生巨大影响。
方法：使用各种数据库和搜索引擎进行了全面的文献分析，纳入现有的最相关的研究文章和数据，并批判性地讨论了实现HPV疫苗接种的足够覆盖率所需解决的操作差距。
结果：本综述重点介绍了现有的HPV疫苗接种策略，需要解决未满足的需求和挑战，以实现适当的实施框架以及实现体面的疫苗接种覆盖率所需的合作。协调良好的疫苗接种策略，重点是少女，如果可能的话，男孩会对世界各地的疾病减少产生巨大影响。
