Abstract:
Three new cadinane sesquiterpenes (1-3) and three known sesquiterpenes were isolated from the stems and branches of Illicium ternstroemioides A. C. Smith. The structures of the new compounds were elucidated by extensive analysis of spectroscopic and HRESIMS data. The structures of illiternins A-C (1-3) were confirmed by single crystal X-ray diffraction, allowing for the determination of their absolute configurations. Compounds 3 and 6 exhibited antiviral activity against Coxsackievirus B3 with IC50 values of 33.3 and 57.7 μM, respectively.
摘要:
三个新的cadinane倍半萜烯(1-3)和三个已知的倍半萜烯从IlliciumternstroemioidesA.C.Smith的茎和分枝中分离出来。通过对光谱和HRESIMS数据的广泛分析,阐明了新化合物的结构。通过单晶X射线衍射证实了文盲A-C(1-3)的结构,允许确定它们的绝对配置。化合物3和6对柯萨奇病毒B3表现出抗病毒活性,IC50值为33.3和57.7μM,分别。