姜黄素通过抑制 miR - 152 - 3p 和激活 FBN1 / TGF - β 通路促进糖尿病足溃疡创面愈合.
关键词: Curcumin Diabetic foot ulcer FBN1 TGF-β miR-152-3p
Mesh : Animals Female Humans Male Rats Adipokines Apoptosis / drug effects Cell Movement / drug effects Cell Proliferation / drug effects Curcumin / pharmacology Diabetic Foot / metabolism genetics drug therapy pathology Disease Models, Animal Fibrillin-1 / genetics metabolism Fibroblasts / metabolism drug effects MicroRNAs / genetics metabolism Rats, Sprague-Dawley Signal Transduction / drug effects Transforming Growth Factor beta / metabolism genetics Wound Healing / drug effects genetics
来 源:
DOI:10.1007/s12033-023-01027-z
PDF(Pubmed)