PDF(Pubmed)
Abstract：
Narrowband ultraviolet-B (NB-UVB) phototherapy is the mainstay of vitiligo therapy. The response can be evaluated using the vitiligo area scoring index (VASI) and repigmentation grade. However, few studies used VASI to evaluate phototherapy response and there are no definitive data on the reduction of VASI. This retrospective descriptive study aimed to determine the characteristics and decrease of VASI in patients with vitiligo after 36 and 48 sessions of NB-UVB phototherapy, conducted at Dr. Sardjito General Hospital, Yogyakarta, from December 2021-June 2022. The most common predilection was on the face (71.43%) and acral (61.90%). The most common responses after 36 and 48 phototherapy sessions were minimally improved (decrease in VASI<10%) and improved (reduction in VASI 10-25%). The mean decrease in VASI was 18% and 22% after 36 and 48 phototherapy sessions, respectively. 9.52% and 6.67% of patients experienced a reduction in VASI >50% after 36 and 48 phototherapy sessions, respectively. VASI assessment can be used to evaluate the response to phototherapy in vitiligo. However, VASI cannot show a reduction in vitiligo with slight repigmentation in slow-response patients.
摘要：
窄带紫外线B（NB-UVB）光疗是白癜风治疗的主要手段。可以使用白癜风面积评分指数（VASI）和色素沉着等级来评估反应。然而,很少有研究使用VASI评估光疗反应,并且没有关于VASI降低的确切数据.这项回顾性描述性研究旨在确定36和48次NB-UVB光疗后白癜风患者VASI的特征和减少，在Sardjito综合医院医生进行，日惹,从2021年12月到2022年6月。最常见的好发是面部（71.43％）和肢端（61.90％）。36次和48次光疗后最常见的反应是最低限度地改善(VASI降低<10%)和改善(VASI降低10-25%)。36次和48次光疗后，VASI平均下降18%和22%，分别。9.52％和6.67％的患者在36和48次光疗后VASI降低>50％，分别。VASI评估可用于评估白癜风对光疗的反应。然而,在慢反应患者中，VASI不能显示白癜风的减少和轻微的色素沉着。
