PDF(Pubmed)
Abstract：
Central airway obstruction often presents with respiratory symptoms identical to those of common respiratory diseases. Diagnosis of central airway obstruction is challenging in clinical practice, especially misdiagnosed as asthma or chronic obstructive pulmonary disease in case of \"normal\" chest X-ray. Here, we reported five central airway obstruction cases: the first and fourth cases misdiagnosed as asthma, the second masquerading as chronic obstructive pulmonary disease exacerbation, the third diagnosed incorrectly with non-resolving pneumonia, and the fifth misdiagnosed as chronic obstructive pulmonary disease. We then analyzed diagnostic clues potentially useful to differentiate central airway obstruction from asthma/chronic obstructive pulmonary disease. A multidisciplinary approach to manage central airway obstruction is essential, particularly selecting judiciously the method of respiratory support due to the high risk of completed airway collapse or obstruction during interventional period.
摘要：
中央气道阻塞通常表现为与常见呼吸道疾病相同的呼吸道症状。中央气道阻塞的诊断在临床实践中具有挑战性。特别是胸部X线检查“正常”时误诊为哮喘或慢性阻塞性肺疾病。这里,我们报告了5例中央气道阻塞病例：第一和第四例误诊为哮喘，第二个伪装成慢性阻塞性肺疾病恶化，第三个被错误诊断为未解决的肺炎，第五例误诊为慢性阻塞性肺疾病。然后，我们分析了可能有助于区分中央气道阻塞和哮喘/慢性阻塞性肺疾病的诊断线索。多学科方法来管理中央气道阻塞是必不可少的，由于在介入期间完全气道塌陷或阻塞的风险很高，因此特别要明智地选择呼吸支持方法。
