关键词: APACHE II Emergency obstetric care Maternal mortality Medical disorders SOFA score

来  源:   DOI:10.1007/s13224-023-01859-4   PDF(Pubmed)

Abstract:
UNASSIGNED: Medical disorders complicating pregnancy have recently emerged as the most common cause for maternal morbidity and mortality and it is important to predict mortality risk when they present in moribund state to emergency obstetric care so as to take and timely effective measures to prevent mortality.
UNASSIGNED: This prospective observational study was conducted over 6 months among pregnant and post-partum women with medical disorders who sought emergency obstetric care at a tertiary care hospital. Severity of morbidity was assessed using SOFA and APACHE II scores at admission.
UNASSIGNED: Of the 128 women, 87.5% were pregnant, and 12.5% were post-partum. Hypertensive disorders, cardiac disorders, neurological disorders and infective disorders were 24.2%, 22.6%, 14% and 9.4%, respectively. The optimal cut-off SOFA score was 2 (AUC = 0.739) with 66% sensitivity and 71% specificity and APACHE II score cut-off was 6 (AUC = 0.732) with a sensitivity of 60% and specificity of 78% in predicting severe maternal morbidity. The median scores of APACHE II and SOFA are 14 and 4, respectively, for non-survivors and for survivors it was 4 and 1.
UNASSIGNED: Hypertensive disorder was the most common medical disorder, but severity was high in cardiac disorder. SOFA and APACHE II scores are good predictors of morbidity and mortality risk.
摘要:
妊娠合并医学疾病最近已成为孕产妇发病和死亡的最常见原因,重要的是要预测死亡风险,当他们出现在垂死状态时,紧急产科护理,以便及时采取有效措施防止死亡。
这项前瞻性观察性研究是在6个月内对在三级医院寻求紧急产科护理的孕妇和产后患者进行的。入院时使用SOFA和APACHEII评分评估发病率的严重程度。
在128位女性中,87.5%怀孕,12.5%为产后。高血压疾病,心脏病,神经系统疾病和感染性疾病占24.2%,22.6%,14%和9.4%,分别。在预测严重孕产妇发病率方面,最佳SOFA分界点为2(AUC=0.739),灵敏度为66%,特异性为71%,APACHEII分界点为6(AUC=0.732),灵敏度为60%,特异性为78%。APACHEII和SOFA的中位数分别为14和4,非幸存者和幸存者分别为4和1.
高血压障碍是最常见的医学障碍,但心脏病的严重程度很高。SOFA和APACHEII评分是发病率和死亡风险的良好预测因子。
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