PDF(Pubmed)
Abstract：
Despite high discontinuation rates for myopia optical interventions, limited attention has been given to the potential rebound effects post-discontinuation. This systematic review aims to assess the extent of the rebound effects following the cessation of common clinical optical myopia-control interventions in children. A comprehensive search of PubMed, Embase, Cochrane CENTRAL, and ClinicalTrials.gov was conducted from inception to October 2023. The rebound effects, defined as changes in the axial length or spherical equivalent during and after treatment cessation, were categorized into four levels. These studies encompassed 703 participants and spanned from 2019 to 2023, with durations of treatment and cessation ranging from 6 months to 3.5 years and from 2 weeks to 5 years, respectively. This review, encompassing 14 studies, revealed a predominant strong rebound effect in orthokeratology (8 studies), a weak rebound effect in multifocal soft contact lenses (4 studies), and a variable rebound effect in peripheral-plus spectacle lenses (2 studies). Notably, with the increasing cessation duration, the rebound effects diminished, potentially linked to the reversal of choroidal thickening and the disappearance of peripheral myopic defocus. In conclusion, a temporal trend of rebound effects exists in all three myopia optical interventions, possibly contributing to their myopia control mechanisms.
摘要：
尽管近视光学干预的中止率很高，停药后的潜在反弹效应受到了有限的关注。本系统综述旨在评估儿童停止常见临床光学近视控制干预后反弹效应的程度。全面搜索PubMed,Embase,科克伦中部,ClinicalTrials.gov从成立到2023年10月进行。反弹效应，定义为在治疗停止期间和之后轴向长度或球形等效物的变化，分为四个级别。这些研究包括703名参与者，从2019年到2023年，治疗和停止的持续时间从6个月到3.5年，从2周到5年不等。分别。这次审查,包括14项研究，揭示了角膜塑形术中主要的强反弹效应(8项研究)，多焦点软性隐形眼镜的弱回弹效应(4项研究)，以及周边加眼镜镜片的可变回弹效应(2项研究)。值得注意的是,随着戒烟持续时间的增加，反弹效应减弱,可能与脉络膜增厚的逆转和周围近视散焦的消失有关。总之,在所有三种近视光学干预中都存在反弹效应的时间趋势，可能有助于他们的近视控制机制。
