关键词: breath research exhaled VOCs exhaled biomarkers exhaled breath exhaled breath condensate

来  源:   DOI:10.4187/respcare.11651   PDF(Pubmed)

Abstract:
Exhaled breath contains an extensive reservoir of biomolecules. The collection of exhaled breath is noninvasive and low risk. Therefore, its testing is an appealing strategy for the discovery of biomarkers of respiratory diseases. In this concise review, we summarize the evidence of exhaled breath tests for airways diseases and respiratory infections. An overview of breath collection methods in both individuals who are spontaneously breathing and those receiving mechanical ventilation is outlined. We also highlight the challenges in exhaled breath testing and areas for future research.
摘要:
呼出气含有大量的生物分子。呼出气的收集是非侵入性和低风险的。因此,它的测试是发现呼吸道疾病生物标志物的一个有吸引力的策略。在这篇简明的评论中,我们总结了呼气测试对气道疾病和呼吸道感染的证据。概述了自发呼吸个体和接受机械通气者的呼吸收集方法。我们还强调了呼气测试中的挑战以及未来研究的领域。
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